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结缔组织病相关性间质性肺病的肺移植治疗现状

Updates in lung transplantation for connective tissue disease-associated interstitial lung disease
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摘要 肺移植是终末期肺病的重要救治手段,目前间质性肺疾病(ILD)接受肺移植的患者日益增多,但其中主要以特发性间质性肺炎为主,而结缔组织病相关间质性肺病(CTD-ILD)亦有大量终末期肺病患者,虽有肺移植的指征,但由于多器官受累,围手术期管理复杂,一直是肺移植领域的难点之一。本文总结了近年来CTD-ILD的肺移植相关治疗进展,以期对受体选择和围手术期管理等临床问题提供相关资料。 Lung transplantation has become a crucial treatment option for patients with end-stage lung disease.In recent years,the number of patients with interstitial lung disease(ILD)undergoing lung transplantation has been steadily increasing,with the majority of these cases involving idiopathic interstitial pneumonia.However,connective tissue disease-related interstitial lung disease(CTD-ILD)also presents a significant number of patients with end-stage lung disease who meet the criteria for lung transplantation.Despite this,due to the involvement of multiple organs and the complexity of perioperative management,CTD-ILD remains one of the major challenges in the field of lung transplantation.This article reviews recent advancements in lung transplantation for CTD-ILD,aiming to provide relevant information on recipient selection and perioperative management for clinicians.
作者 刘虎 贺瑞卿 谢敏 LIU Hu;HE Rui-qing;XIE Min(Department of Pulmonary and Critical Care Medicine,Shanxi Bethune Hospital,Shanxi Taiyuan,030032,China;Department of Pulmonary and Critical Care Medicine,Tongji Hospital,Tongji Medical College,Huazhong University of Science and Technology,Hubei Wuhan 430030,China)
出处 《内科急危重症杂志》 2024年第5期451-454,共4页 Journal of Critical Care In Internal Medicine
关键词 结缔组织病 间质性肺病 肺移植 Connective tissue disease Interstitial lung disease Lung transplantation
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