摘要
结缔组织病相关间质性肺病(CTD-ILD)发病率高,生存时间明显缩短。早期检测、在疾病过程中动态评估疾病进展、及时给予适当的治疗可以改善CTD-ILD患者的生活质量及预后。一些简单易得的方法可能在疾病早期就检测出结缔组织病患者合并的间质性肺病。为CTD-ILD患者制定治疗方案时,一些特异性较好的预后因素(如性别、年龄等一般情况,肺功能,高分辨率CT,病理类型,复合死亡预测模型等)可能会让治疗更加有针对性。随着新的治疗方法的出现,未来的临床试验可能会提出更好的管理CTD-ILD的方案。本文对近几年CTD-ILD诊断、病情评估及治疗的研究进展作一综述。
The incidence of connective tissue disease-associated interstitial lung disease(CTD-ILD)is high,and the survival time is shortened.Early detection,the dynamic assessment of disease progression in the disease process,timely and appropriate treatment can improve the quality of life and prognosis of CTD-ILD patients.Some simple and easy methods may detect interstitial lung disease in patients with connective tissue disease at an early stage of the disease.When developing treatment options for patients with CTD-ILD,some of the more specific prognostic factors(general condition such as gender and age,pulmonary function,high-resolution computed tomography,pathological type,combined death prediction model,etc.)may make treatment more specific.With the advent of new therapies,future clinical trials may suggest better ways to manage CTD-ILD.This article reviews the recent advances in the diagnosis,assessment and treatment of CTD-ILD.
作者
黄莎
李凡
Huang Sha;Li Fan(Department of Geriatrics,the Fifth People′s Hospital of Zigong City,Zigong 643020,China)
出处
《国际呼吸杂志》
2020年第15期1160-1167,共8页
International Journal of Respiration
关键词
结缔组织病相关间质性肺病
结缔组织疾病
间质性肺病
诊断
治疗
Connective tissue disease-associated interstitial lung disease
Connective tissue disease
Interstitial lung disease
Diagnosis
Treatment
