摘要
目的:分析2019–2023年广州市番禺区无偿献血者血液不合格情况及分布特征,为规范无偿献血者招募策略,提高采集血液合格率提供依据。方法:选取2019–2023年广州市番禺区中心血站采集的166205份无偿献血者的血液标本为研究对象进行血液检测,比较2019–2023年无偿献血者的丙氨酸氨基转移酶(ALT)、乙型肝炎表面抗原(HBsAg)、丙型肝炎病毒抗体(抗–HCV)、梅毒螺旋体特异性抗体(抗–Tp)、人类免疫缺陷病毒(HIV)抗原(Ag)/抗体(Ab)指标不合格数据,并比较不同年份、性别、年龄、学历及不同职业人群的不合格率情况。结果:2019–2023年总检测标本数166205份,标本合格数为157271份,标本总不合格率为5.38%。其中ALT不合格率占比最高,为4.04%,献血者检测不合格率呈逐年上升趋势(χ^(2)=366.488,P<0.001),主要由ALT不合格率上升造成(χ^(2)=487.290,P<0.001)。不同性别无偿献血者血液检测的总不合格率及ALT、HBsAg、抗–HCV、HIV Ag/Ab不合格率比较,差异均具有统计学意义(P<0.05),男、女性检测项目不合项中,ALT不合格率占比最高,分别为5.32%、1.22%;不同年龄无偿献血者血液检测的总不合格率及ALT、HBsAg、抗–Tp不合格率比较,差异均具有统计学意义(P<0.001);不同学历无偿献血者检测的总不合格率数及ALT、HBsAg、抗–Tp及HIV Ag/Ab不合格率比较,差异均具有统计学意义(P<0.05);不同职业无偿献血者检测的总不合格率及ALT、HBsAg、抗–Tp及HIV Ag/Ab不合格率比较,差异均具有统计学意义(P<0.05)。结论:2019–2023年广州市番禺区无偿献血人群中,血液检测不合格率呈逐年上升趋势。男性、26~35岁、初中及以下学历者和农民的血液检测不合格率比例较高,ALT、抗–HCV和HBsAg是血液检测不合格的主要项目。
Objective To analyze the unqualified blood situation and distribution characteristics of unpaid blood donors in Panyu District of Guangzhou from 2019 to 2023,so as to provide a basis for regulating the recruitment strategy of unpaid blood donors and improving the qualified rate of blood collection.Methods Blood samples of 166,205 unpaid blood donors collected from Guangzhou Panyu District Central Blood Station from 2019 to 2023 were selected as the research objects for blood testing.To compare the unqualified data of alanine aminotransferase(ALT),hepatitis B surface antigen(HBsAg),hepatitis C virus antibody(anti-HCV),treponema pallidum specific antibody(anti-TP),and human immunodeficiency virus(HIV)antigen(Ag)/antibody(Ab)among unpaid blood donors from 2019 to 2023.The failure rates of different years,gender,age,educational background and different occupations were compared.Results From 2019 to 2023,a total of 166,205 specimens were detected,157,271 specimens were qualified,and the total unqualified rate was 5.38%.Among them,the proportion of unqualified ALT was the highest,which was 4.04%.The unqualified rate of blood donors showed an increasing trend year by year(χ^(2)=366.488,P<0.001),which was mainly caused by the increase of unqualified ALT rate(χ^(2)=487.290,P<0.001).The total failure rate and the failure rate of ALT,HBsAg,anti-HCV and HIV Ag/Ab in blood tests of different genders were statistically significant(P<0.05).Among the non-conforming items in male and female blood tests,the ALT failure rate accounted for the highest proportion,which was 5.32%and 1.22%,respectively.There were statistically significant differences in the total failure rate and ALT,HBsAg and anti-TP failure rates among unpaid blood donors of different ages(P<0.001).There were statistically significant differences in the total unqualified rate and the unqualified rate of ALT,HBsAg,anti-TP and HIV Ag/Ab among unpaid blood donors with different educational backgrounds(P<0.05).There were statistically significant differences in the tot
作者
黎添华
马伟文
劳丽嫦
谢敬文
LI Tianhua;MA Weiwen;LAO Lichang;XIE Jingwen(Guangzhou Panyu District Central Blood Station,Guangdong Guangzhou 511400)
出处
《深圳中西医结合杂志》
2024年第15期26-30,共5页
Shenzhen Journal of Integrated Traditional Chinese and Western Medicine
关键词
无偿献血
血液不合格
广州市番禺区
Voluntary blood donation
Blood is not qualified
Panyu District of Guangzhou
