摘要
目的:观察滋阴补阳调经汤加减治疗肾虚型多囊卵巢综合征(PCOS)所致不孕症的临床疗效。方法:选择肾虚型PCOS所致不孕症患者88例,采用随机数字表法分为对照组和观察组各44例。2组均给予生活指导,调整饮食结构,叮嘱患者适当进行有氧运动,保持心情愉快,避免熬夜,控制体质量。对照组给予枸橼酸氯米芬片治疗,观察组在对照组基础上予滋阴补阳调经汤加减治疗。3个月经周期为1个疗程,2组均治疗2个疗程。评价2组临床疗效,比较2组治疗前后中医证候评分、性激素指标[卵泡刺激素(FSH)、黄体生成素(LH)、雌二醇(E_(2))、睾酮(T)]及子宫体积、卵巢体积、卵泡数目变化。随访3个月,统计2组的妊娠率。结果:观察组总有效率为93.18%,高于对照组77.27%(P<0.05)。治疗后,2组各项中医证候评分较治疗前降低(P<0.05),且观察组各项中医证候评分低于对照组(P<0.05)。治疗后,2组FSH、E_(2)较治疗前升高,且观察组高于对照组(P<0.05);2组LH、T较治疗前降低,且观察组低于对照组(P<0.05)。治疗后,2组子宫体积较治疗前增大,观察组大于对照组(P<0.05);2组卵巢体积及卵泡数目较治疗前减小,观察组小于对照组(P<0.05)。随访3个月,观察组妊娠率为75.00%,高于对照组52.27%(P<0.05)。结论:滋阴补阳调经汤加减治疗肾虚型PCOS所致的不孕症可有效改善患者临床症状,调节性激素水平,改善子宫、卵巢体积,提高妊娠率。
Objective:To observe the clinical effect of modified Ziyin Buyang Tiaojing Decoction on infertility caused by polycystic ovary syndrome(PCOS)of kidney deficiency type.Methods:A total of 88 patients with infertility caused by PCOS of kidney deficiency type were selected and divided into the control group and the observation group by random number table method,with 44 cases in each group.Both groups were given life guidance and adjustment of dietary structure;they were advised to engage in aerobic exercise appropriately,maintain a good mood,avoid staying up late,and control body mass.The control group was treated with Clomiphene Citrate Tablets,while the observation group was treated with modified Ziyin Buyang Tiaojing Decoction on the basis of the control group.Three menstrual cycles constitute one course of treatment,with both groups receiving two courses of treatment.Clinical effects in the two groups were evaluated.The changes in traditional Chinese medicine(TCM)syndrome scores,sex hormone indicators[follicle stimulating hormone(FSH),luteinizing hormone(LH),estradiol(E_(2)),and testosterone(T)],uterine volume,ovarian volume,and follicle number before and after treatment were compared between the two groups.After three months of follow-up,the pregnancy rates in the two groups were counted.Results:The total effective rate was 93.18%in the observation group,which was higher than that of 77.27%in the control group(P<0.05).After treatment,TCM syndrome scores in the two groups were decreased when compared with those before treatment(P<0.05),and each TCM syndrome score in the observation group was lower than that in the control group(P<0.05).After treatment,FSH and E_(2) in the two groups were increased when compared with those before treatment,and FSH and E_(2) in the observation group were higher than those in the control group(P<0.05);LH and T in the two groups were decreased,and LH and T in the observation group were lower than those in the control group(P<0.05).After treatment,uterine volume in the two groups wer
作者
李燕
徐建阳
LI Yan;XU Jianyang(Department of Gynaecology and Obstetrics,Wenling Hospital of Traditional Chinese Medicine,Wenling Zhejiang 317500,China;Department of Traditional Chinese Medicine,Wenling Hospital of Traditional Chinese Medicine,Wenling Zhejiang 317500,China)
出处
《新中医》
CAS
2024年第19期101-105,共5页
New Chinese Medicine
关键词
多囊卵巢综合征
不孕症
滋阴补阳调经汤
中医证候评分
性激素
妊娠率
Polycystic ovary syndrome
Infertility
Ziyin Buyang Tiaojing Decoction
Traditional Chinese Medicine syndrome scores
Sex hormones
Pregnancy rate
