摘要
目的:观察丹桂止氛汤加味治疗妊娠期糖尿病(GDM)的临床疗效及对妊娠结局的影响。方法:选取GDM患者62例,按随机数字表法分为对照组和联合组各31例。对照组参考GDM指南行常规治疗方案,联合组在对照组基础上予丹桂止氛汤加味治疗。2组均治疗8周。评价2组临床疗效,比较2组血糖指标、胰岛素抵抗指标及妊娠结局。结果:治疗后,联合组总有效率为96.77%,高于对照组74.19%(P<0.05)。治疗后,2组空腹血糖(FBG)、餐后2h血糖(P2hBG)、糖化血红蛋白(HbA1c)较治疗前降低(P<0.05),且联合组FBG、P2hBG、HbA1c低于对照组(P<0.05)。治疗后,2组空腹胰岛素(FINS)、胰岛素抵抗指数(HOMA-IR)较治疗前降低(P<0.05),且联合组FINS、HOMA-IR低于对照组(P<0.05)。联合组剖宫产率、胎儿呼吸窘迫综合征发生率低于对照组(P<0.05)。结论:丹桂止氛汤加味治疗GDM疗效明显,可改善患者的血糖水平与胰岛素抵抗,减少不良妊娠结局。
Objective:To observe the clinical effect of modified Dangui Zhifen Decoction in the treatment of gestational diabetes mellitus(GDM)and its effect on pregnancy outcome.Methods:A total of 62 GDM patients were selected and divided into the control group and the combination group according to the random number table method,with 31 cases in each group.The control group received routine treatment according to the GDM guidelines,and the combination group received modified Dangui Zhifen Decoction on the basis of the treatment of the control group.Both groups were treated for eight weeks.Evaluated the clinical effects of the two groups,and compared the blood glucose indicators,insulin resistance indicators,and pregnancy outcomes.Results:After treatment,the total effective rate was 96.77%in the combination group,which was higher than that of 74.19%in the control group(P<0.05).After treatment,the fasting blood glucose(FBG),2-hour postprandial blood glucose(P2hBG),and glycated hemoglobin(HbA1c)in the two groups were decreased when compared with those before treatment(P<0.05),and the combination group had lower levels of FBG,P2hBG,and HbA1c than the control group(P<0.05).After treatment,the fasting insulin(FINS)and insulin resistance index(HOMA-IR)in the two groups were decreased when compared with those before treatment(P<0.05),and the FINS and HOMA-IR in the combination group were lower than those in the control group(P<0.05).The cesarean section rate and incidence of fetal respiratory distress syndrome in the combination group were lower than those in the control group(P<0.05).Conclusion:Modified Dangui Zhifen Decoction for GDM has a significant clinical effect,which can improve the blood glucose levels and insulin resistance of patients,and reduce adverse pregnancy outcomes.
作者
郑丽萍
舒莉
郑元锋
ZHENG Liping;SHU Li;ZHENG Yuanfeng(Obstetrics and Gynecology Department,Quzhou Kecheng District People's Hospital,Quzhou Zhejiang 324000,China;Department of Traditional Chinese Medicine,QuzhouKecheng District People's Hospital,Quzhou Zhejiang 324000,China)
出处
《新中医》
CAS
2024年第19期34-38,共5页
New Chinese Medicine
关键词
妊娠糖尿病
丹桂止氛汤
妊娠结局
血糖
胰岛素抵抗
Gestational diabetes mellitus
Dangui Zhifen Decoction
Pregnancy outcome
Blood glucose
Insulin resistance
