摘要
目的探讨腹腔镜下子宫肌瘤剔除术治疗子宫肌瘤的临床效果及对应激反应的影响。方法选取2020年10月至2023年10月乌海市妇幼保健院收治的200例子宫肌瘤患者作为研究对象,采用随机数字表法分为对照组与研究组,每组各100例。对照组实施传统开腹手术治疗,研究组实施腹腔镜下子宫肌瘤剔除术。比较两组围手术期指标、炎症因子水平、应激反应指标及并发症发生情况。结果研究组手术时间长于对照组,术后首次下床、术后肛门首次排气、住院时间短于对照组,术中出血量少于对照组,差异有统计学意义(P<0.05)。治疗后,研究组C反应蛋白、白介素-2、白介素-6水平均低于对照组,差异有统计学意义(P<0.05)。治疗后,研究组肾上腺素、去甲肾上腺素、皮质醇及多巴胺水平均低于对照组,差异有统计学意义(P<0.05)。研究组并发症总发生率低于对照组,差异有统计学意义(P<0.05)。结论腹腔镜下子宫肌瘤剔除术治疗子宫肌瘤的临床效果良好,可有效改善炎症因子水平及围手术期指标,降低应激反应及并发症发生风险。
Objective To explore the clinical effect of laparoscopic myomectomy in the treatment of uterine fibroids and its impact on stress response.Methods A total of 200 patients with uterine fibroids admitted to Wuhai Maternity and Child Health Care Hospital from October 2020 to October 2023 were selected as the study objects.All the patients were divided into the control group and the study group using the random number table method,with 100 cases in each group.The control group was treated with traditional laparotomy surgery,while the study group was treated with laparoscopic myomectomy.The perioperative indicators,levels of inflammatory factors,stress response indicators,and incidence of complications were compared between the two groups.Results The surgical time of the study group was longer than that of the control group,the time of getting out of bed for the first time after surgery,first postoperative anal exhaust,and hospital stay was shorter than that in the control group,the intraoperative bleeding volume was less than that of the control group,and the differences were statistically significant(P<0.05).After treatment,the levels of C-reactive protein,interleukin-2,and interleukin-6 in the study group were lower than those in the control group,and the differences were statistically significant(P<0.05).After treatment,the levels of epinephrine,norepinephrine,cortisol,and dopamine in the study group were lower than those in the control group,and the differences werestatistically significant(P<0.05).The total incidence of complications in the study group was lower than that in the control group,and the difference was statistically significant(P<0.05).Conclusion The clinical effect of laparoscopic myomectomy in the treatment of uterine fibroids is good,which can effectively improve the levels of inflammatory factors and perioperative indicators,and reduce the risk of stress res ponse and complications.
作者
颜鹏超
杨婧娟
YAN Pengchao;YANG Jingjuan(Department of Gynaecology,Wuhai Maternity and Child Health Care Hospital,Inner Mongolia Autonomous Region,Wuhai 016099,China)
出处
《妇儿健康导刊》
2024年第16期41-44,49,共5页
JOURNAL OF WOMEN AND CHILDREN'S HEALTH GUIDE
