摘要
目的探讨腹腔镜子宫肌瘤剔除术治疗子宫肌瘤的临床效果及对患者应激反应的影响。方法回顾性分析96例子宫肌瘤患者的临床资料,按照手术方式的不同分为传统组和微创组各48例。传统组行开腹子宫肌瘤剔除术治疗,微创组行腹腔镜子宫肌瘤剔除术。比较两组患者手术指标、恢复情况、应激反应指标及治疗过程中的并发症发生情况。结果微创组的手术时间明显长于传统组,但术中出血量明显小于传统组,术后排气、排便时间及住院时间明显短于传统组(均P<0.05)。术后,两组去甲肾上腺素(NE)、P物质(SP)和肾上腺素(E)水平均明显上升,但微创组低于传统组;两组谷胱甘肽过氧化物酶(GSH-Px)水平均下降,但微创组高于传统组(均P<0.05)。微创组患者的并发症发生率为4.17%,明显低于传统组的20.83%(均P<0.05)。结论应用腹腔镜技术治疗子宫肌瘤,术中出血量少,术后恢复快,且能明显缓解患者的应激反应,降低并发症发生率,值得临床推广。
Objective To investigate the clinical effect of laparoscopic myomectomy and its effect on stress response in patients with hysteromyoma.Methods Clinical data of 96 patients with hysteromyoma were analyzed retrospectively.Patients were divided into traditional group or minimally invasive group according to their operation methods,with 48 cases in each group.The traditional group was treated with open surgery of myomectomy,while the minimally invasive group was treated with laparoscopic myomectomy.The operative index,condition of recovery,stress response index,and the incidence of complications during treatment were compared between the two groups.Results Compared to the traditional group,the minimally invasive group had significantly longer operation duration,but significantly less intraoperative blood loss,time of postoperative exhaust and defecation,and hospital stay(all P<0.05).After operation,the levels of norepinephrine(NE),substance P(SP),epinephrine(E)increased significantly in both groups,with the levels lower in the minimally invasive group than in the traditional group,while the level of glutathione peroxidase(GSH-Px)decreased significantly in both groups,with the level was significantly higher in the minimally invasive group than in the traditional group(all P<0.05).The incidence of complications in the minimally invasive group was 4.17%,which was significantly lower than 20.83%in the traditional group(all P<0.05).Conclusion The application of laparoscopic technique in the treatment of hysteromyoma is associated with less intraoperative blood loss,faster postoperative recovery.It can obviously alleviate the stress response of patients,and reduce the incidence of complications.It is worthy of clinical promotion.
作者
蒋红梅
JIANG Hongmei(Department of Obstetrics and Gynecology,Central Hospital of Jiamusi,Jiamusi 154002,Heilongjiang,China)
出处
《微创医学》
2019年第5期596-598,682,共4页
Journal of Minimally Invasive Medicine
