摘要
目的对比Sonazoid超声造影与普美显增强MRI对肝细胞肝癌(HCC)的诊断价值。方法选取我院肝脏占位性病变患者43例,共计55个病灶,其中HCC 41个,良性病灶14个。观察HCC与良性病灶的Sonazoid超声造影及普美显增强MRI图像特征,比较二者对HCC的诊断准确率、灵敏度、特异度;采用Kappa检验分析二者的一致性。结果HCC与良性病灶在动脉期、延迟期及血管后期(Kupffer期)的超声造影增强特征比较差异均有统计学意义(均P<0.05),其中HCC动脉期以高增强为主(75.61%),延迟期均呈等或低增强,Kupffer期以低增强为主(85.37%)。HCC与良性病灶在动脉期和肝胆期的增强MRI增强特征比较差异均有统计学意义(均P<0.05),其中HCC动脉期以高信号为主(65.85%),肝胆期以低信号为主(73.17%)。Sonazoid超声造影和普美显增强MRI对HCC的诊断准确率、灵敏度、特异度分别为87.27%、90.24%、78.57%和90.91%、92.68%、85.71%,二者比较差异均无统计学意义。Sonazoid超声造影与普美显增强MRI诊断HCC的一致性好(Kappa=0.908)。结论Sonazoid超声造影对HCC的诊断效能与普美显增强MRI相当。
Objective To compare the diagnostic value of Sonazoid contrast-enhanced ultrasound and gadoxetic acid-enhanced MRI in hepatocellular carcinoma(HCC).Methods Forty-three patients with liver space occupying lesions were selected from our hospital(55 lesions),including 41 HCC and 14 benign lesions.The imaging features in both Sonazoid contrastenhanced ultrasound and gadoxetic acid-enhanced MRI were observed.The diagnostic accuracy,sensitivity and specificity of Sonazoid contrast-enhanced ultrasound and gadoxetic acid-enhanced MRI in the diagnosis of HCC were compared,respectively,and Kappa test was performed to analyse their consistency.Results There were statistically significant differences in the enhancement characteristics of Sonazoid contrast-enhanced ultrasound between HCC and benign lesions in the arterial phase,delayed phase and late vascular(Kupffer phase,all P<0.05).Among them,HCC mainly showed high enhancement in the arterial phase(75.61%),equal or low enhancement in the delayed phase,and mainly showed low enhancement in the Kupffer phase(85.37%).There were statistically significant differences in the enhancement characteristics of gadoxetic acid-enhanced MRI between HCC and benign lesions in the arterial and hepatobiliary phases(both P<0.05).Among them,high signal was mainly observed in the HCC arterial phase(65.85%),and low signal was mainly observed in the hepatobiliary phase(73.17%).The diagnostic accuracy,sensitivity and specificity of Sonazoid contrast-enhanced ultrasound and gadoxetic acid-enhanced MRI in diagnosing HCC were 87.27%,90.24%,78.57% and 90.91%,92.68%,85.71%,respectively,and there were no statistically significant difference between the two imaging techniques.The consistency between Sonazoid contrast-enhanced ultrasound and gadoxetic acid-enhanced MRI in the diagnosis of HCC was good(Kappa=0.908).Conclusion The diagnostic efficacy of Sonazoid contrast-enhanced ultrasound and gadoxetic acid-enhanced MRI in HCC is equivalent.
作者
张雨
汤群锋
吴鸣宇
杨树东
周锋盛
ZHANG Yu;TANG Qunfeng;WU Mingyu;YANG Shudong;ZHOU Fengsheng(Department of Ultrasound Medicine,the Affiliated Wuxi People’s Hospital of Nanjing Medical University,Wuxi People’s Hospital,Wuxi Medical Center,Nanjing Medical University,Jiangsu 214023,China)
出处
《临床超声医学杂志》
CSCD
2024年第8期630-635,共6页
Journal of Clinical Ultrasound in Medicine
基金
无锡市卫健委科研项目(Q202142)。
