摘要
目的探讨联合检验高敏肌钙蛋白Ⅰ(High-sensitive Cardiac TroponinⅠ,hs-cTnⅠ)、肌红蛋白(Myoglobin,Myo)及心肌酶谱在心肌梗死中的诊断效能。方法选取仁怀市人民医院于2021年6月—2022年6月收治的100例心肌梗死患者及100名健康体检者分别为观察组、对照组,均采血检测hs-cTnI、Myo、肌酸激酶同工酶(Creatine Kinase-MB,CK-MB)水平,比较两组血清hs-cTnI、Myo、CK-MB水平差异,并绘制受试者操作特征(Receiver Operating Characteristic,ROC)曲线分析血清各指标及联合检测在心肌梗死中的诊断效能。结果观察组血清hs-cTnI、Myo、CK-MB水平为(0.28±0.05)μg/L、(95.63±7.25)μg/L、(75.63±6.35)U/L,高于对照组的(0.04±0.01)μg/L、(41.47±4.31)μg/L、(20.32±2.14)U/L,差异有统计学意义(t=47.068、64.213、82.541,P均<0.05)。ROC曲线显示,血清hs-cTnI、Myo、CK-MB联合检测诊断心肌梗死价值最高。结论血清hs-cTnI、Myo、CK-MB在心肌梗死诊断中具有一定价值,联合检测价值更高,有助于患者尽早开展针对性治疗,以改善预后。
Objective To investigate the diagnostic efficacy of the combined test of high-sensitive cardiac troponin I(hs-cTnI),myoglobin(Myo)and cardiac enzyme profile in myocardial infarction.Methods A total of 100 patients with myocardial infarction and 100 healthy medical checkups admitted to Renhuai People′s Hospital from June 2021 to June 2022 were selected as observation group and control group,respectively.Blood was collected to test the levels of hs-cTnI,Myo,and creatine kinase-MB(CK-MB),and the differences in the levels of serum hs-cTnI,Myo,and CK-MB between the two groups were compared,and receiver operating characteristic(ROC)curves were plotted to analyze the diagnostic efficacy of serum indexes and the combination of tests in myocardial infarction.Results The serum hs-cTnI,Myo,and CK-MB levels in the observation group were(0.28±0.05)μg/L,(95.63±7.25)μg/L,and(75.63±6.35)U/L,which were higher than those in the control group(0.04±0.01)μg/L,(41.47±4.31)μg/L,and(20.32±2.14)U/L,and the differences were statistically significant(t=47.068,64.213,82.541,all P<0.05).ROC curve showed that the combined detection of serum hs-cTnI,Myo,and CK-MB had the highest value in diagnosing myocardial infarction.Conclusion Serum hs-cTnI,Myo,and CK-MB have certain value in the diagnosis of myocardial infarction,and the value of combined detection is higher,which can help patients carry out targeted treatment as early as possible in order to improve the prognosis.
作者
刘吉能
李道霞
熊欢欢
周小琴
赵立群
LIU Jineng;LI Daoxia;XIONG Huanhuan;ZHOU Xiaoqin;ZHAO Liqun(Department of Laboratory,Renhuai People′s Hospital,Renhuai,Guizhou Province,564500 China)
出处
《系统医学》
2024年第8期89-91,95,共4页
Systems Medicine
关键词
心肌梗死
高敏肌钙蛋白I
肌红蛋白
心肌酶谱
诊断效能
Myocardial infarction
High-sensitivity cardiac troponin I
Myoglobin
Cardiac enzyme profile
Diagnostic efficacy
