摘要
宫颈癌作为最常见的妇科恶性肿瘤之一,严重危害女性健康和生命安全。我国作为宫颈癌高发国家,发病率和死亡率一直居高不下,并且逐渐呈现出年轻化趋势。宫颈癌的发生发展与人乳头瘤病毒感染、DNA甲基化、RNA异常表达等诸多因素相关。近年来随着技术的发展革新,宫颈癌相关发病机制不断研究深入,尤其是基因测序技术、分子检测技术的逐渐成熟,宫颈癌新型生物标志物层出不穷,本文通过对新型宫颈癌生物学标记物表达特点以及作用机制进行综述,旨在为科学化制定宫颈癌筛查指标作参考。
Cervical cancer is one of the most common gynecological malignant tumors,which seriously endangers women's health and life safety.As a country with a high incidence of cervical cancer,the incidence and mortality of cervical cancer in China have been high,and gradually showing a younger trend.The occurrence and development of cervical cancer is related to human papillomavirus infection,DNA methylation,abnormal expression of RNA and many other factors.In recent years,with the development and innovation of technology,the pathogenesis of cervical cancer has been deeply studied,especially the gradual maturity of gene sequencing technology and molecular detection technology,and new biomarkers of cervical cancer emerge in endlessly,this article reviews the expression characteristics and mechanism of new cervical cancer biomarkers,aiming to provide reference for the scientific development of cervical cancer screening indicators.
作者
李新倩
辛艳
Li Xinqian;Xin Yan(Department of Gynecology,Rizhao People's Hospital,Rizhao Shandong,276800,China)
出处
《中外女性健康研究》
2024年第5期11-13,共3页
Women＇s Health Research
