摘要
目的分析翼状胬肉切除联合角膜缘干细胞移植的临床疗效。方法回顾性选取2021年1月—2023年1月尤溪县总医院收治的80例老年翼状胬肉患者的临床资料,40例采用单纯翼状胬肉切除术治疗患者作为对照组,40例加用角膜缘干细胞移植治疗患者作为观察组。比较两组治疗效果。结果治疗后,观察组泪膜破裂时间、基础泪液分泌测定高于对照组,角结膜荧光素染色评分低于对照组,差异有统计学意义(P均<0.05)。治疗后3、7 d,观察组结膜水肿、结膜充血评分低于对照组,差异有统计学意义(P均<0.05)。观察组视觉功能指标改善优于对照组,差异有统计学意义(P<0.05)。观察组并发症发生率为12.50%,复发率为5.00%,低于对照组,差异有统计学意义(χ^(2)=4.588、5.165,P均<0.05)。结论翼状胬肉切除联合角膜缘干细胞移植可有效改善老年翼状胬肉患者泪膜稳定性和视觉功能,降低并发症发生率及复发率。
Objective To analyze the clinical effect of pterygium excision combined with limbal stem cell transplantation.Methods The clinical data of 80 cases of elderly pterygium patients admitted to Youxi County General Hospital from January 2021 to January 2023 were retrospectively selected,40 patients treated with simple pterygium excision as the control group,and 40 patients treated with the addition of corneal limbal stem cell transplantation as the observation group.The treatment effects of the two groups were compared.Results After treatment,the tear film rupture time and basal tear secretion measurement of the observation group were higher than that of the control group,and the corneal conjunctival fluorescein staining score was lower than that of the control group,and the difference was statistically significant(all P<0.05).Conjunctival edema and conjunctival congestion scores of the observation group were lower than those of the control group at 3 d and 7 d after treatment,and the differences were statistically significant(all P<0.05).The improvement of visual function indexes in the observation group was better than that in the control group,and the difference was statistically significant(P<0.05).The complication rate of the observation group was 12.50%and the recurrence rate was 5.00%,which were lower than those of the control group,and the differences were statistically significant(χ^(2)=4.588,5.165,both P<0.05).Conclusion Pterygium excision combined with limbal stem cell transplantation can effectively improve tear film stability and visual function in elderly patients with pterygium,and reduce the incidence of complications and recurrence.
作者
宋琳琳
谢秀缎
郑庆炜
SONG Linlin;XIE Xiuduan;ZHENG Qingwei(Department of Ophthalmology and Otolaryngology,Youxi County General Hospital,Sanming,Fujian Province,365100 China)
出处
《中外医疗》
2024年第3期21-25,共5页
China & Foreign Medical Treatment
关键词
老年翼状胬肉
角膜缘干细胞移植
泪膜稳定性
视觉功能
复发率
Pterygium of elderly
Limbal stem cell transplantation
Tear film stability
Visual function
Recurrence rate
