摘要
目的 考察火针密刺法联合身痛逐瘀汤对风痰瘀络型膝骨性关节炎患者的临床疗效。方法 62例患者随机分为对照组和观察组,每组31例,对照组给予身痛逐瘀汤,观察组在对照组基础上加用火针密刺法,疗程2周。检测临床疗效、中医证候评分、VAS评分、Lysholm评分、WOMAC评分、血清学指标(MMP-3、IL-6、TNF-α)、不良反应发生率变化。结果 观察组总有效率高于对照组(P<0.05)。治疗后,2组中医证候评分、VAS评分、WOMAC评分、血清学指标降低(P<0.05),Lysholm评分升高(P<0.05),以观察组更明显(P<0.05)。2组不良反应发生率比较,差异无统计学意义(P>0.05)。结论 火针密刺法联合身痛逐瘀汤可安全有效地缓解风痰瘀络型膝骨性关节炎患者临床症状及疼痛,改善膝关节功能,提高临床疗效,调节机体炎性因子水平。
AIM To investigate the clinical effects of Dense Fire-Needling combined with Shentong Zhuyu Decoction on patients with knee osteoarthritis of Wind-Phlegm Blocking Collateral Pattern.METHODS Sixty-two patients were randomly assigned into control group(31 cases)for 2-week intervention of Shentong Zhuyu Decoction,and observation group(31 cases)for 2-week intervention of both Dense Fire-Needling and Shentong Zhuyu Decoction.The changes in clinical effects,TCM syndrome scores,VAS score,Lysholm score,WOMAC score,serological indices(MMP-3,IL-6,TNF-α)and incidence of adverse reactions were detected.RESULTS The observation group demonstrated higher total effective rate than the control group(P<0.05).After the treatment,the two groups displayed decreased TCM syndrome scores,VAS score,WOMAC score,serological indices(P<0.05),and increased Lysholm score(P<0.05),especially for the observation group(P<0.05).No significant difference in incidence of adverse reactions was found between the two groups(P>0.05).CONCLUSION For the patients of Wind-Phlegm Blocking Collateral Pattern,Dense Fire-Needling combined with Shentong Zhuyu Decoction can safely and effectively relieve clinical symptoms and pain,improve knee joint functions,enhance clinical effects,and regulate body inflammatory factor levels.
作者
陈丹
王成
邢海辉
CHEN Dan;WANG Cheng;XING Hai-hui(Department of Rehabilitation Medicine,People’s Hospital of Xuancheng City,Xuancheng 242000,China;Department of Traditional Chinese Medicine,People’s Hospital of Xuancheng City,Xuancheng 242000,China;Department of Acupuncture&Moxibustion,Nanjing Gaochun Hospital of Traditional Chinese Medicine,Nanjing 211300,China)
出处
《中成药》
CAS
CSCD
北大核心
2024年第3期826-830,共5页
Chinese Traditional Patent Medicine
基金
安徽省重点研究与开发计划项目(202104j07020008)。
关键词
身痛逐瘀汤
火针密刺法
膝骨性关节炎
风痰瘀络
Shentong Zhuyu Decoction
Dense Fire-Needling
knee osteoarthritis
Wind-Phlegm Blocking Collateral
