摘要
目的 探讨团体认知行为干预(cognitive behavioral therapy, CBT)对宫颈高危型人乳头瘤病毒(high risk human papillomavirus, HR-HPV)持续感染患者临床转归的影响,构建针对情绪障碍的HR-HPV持续感染患者的系统性心理干预治疗方案。方法 选取HR-HPV持续感染合并情绪障碍患者,按照随机数字表法分为干预组(n=44)和对照组(n=45):对照组给予健康宣教、随访监测,干预组在此基础上给予CBT干预,比较两组的临床转归及心理量表评分。结果 随访6月及12月,HR-HPV感染消退率干预组高于对照组;而HR-HPV持续感染率及进展率干预组低于对照组(P<0.05)。抑郁症筛查量表(PHQ-9)及广泛性焦虑量表(GAD-7)评分,干预结束后即刻、随访6月及12月,干预组均低于对照组(P<0.05);干预组干预结束后即刻、随访6月及12月评分均低于干预前(P<0.05);对照组干预前后评分差异无统计学意义(P>0.05)。结论 HR-HPV持续感染患者进行系统性心理干预治疗,有助于HR-HPV感染消退。
Objective To explore the effect of group cognitive behavioral therapy(CBT)on the clinical outcome of patients with persistent high-risk human papillomavirus(HR-HPV)infection,and to construct a systematic psychological intervention treatment program for persistent HR-HPV infection patients with emotional disorders.Methods A total of 96 patients with persistent HR-HPV infection complicated with emotional disorder admitted in our hospital from September 2021 to March 2022 were recruited,and then randomly divided into an intervention group(n=44)and a control group(n=45)after 5 of them were excluded due to personal reason.The control group received health education and follow-up monitoring,and the intervention group received group CBT intervention additionally.Their clinical outcomes and psychological scale scores were compared between the 2 groups.Results In a follow-up for 6 and 12 months,the regression rate of HR-HPV infection was higher,and the sustained infection rate and progression rate of HR-HPV in the intervention group than the control group(P<0.05).The intervention group also obtained lower scores of Nine-Item Patient Health Questionnaire(PHQ-9)and generalized anxiety scale(GAD-7)immediately after the intervention,and 6 and 12 months in follow-up for when compared with the control group(P<0.05).And the scores at above time points were statistically lower than those before intervention in the intervention group(P<0.05),but no such differences were observed in the control group(P>0.05).Conclusion Systematic psychological intervention treatment is beneficial to HR-HPV infection subside for patients with persistent HR-HPV infection.
作者
龙馨
蒋成刚
韩容
朱红锦
陈彦秋
杨君
LONG Xin;JIANG Chenggang;HAN Rong;ZHU Hongjin;CHEN Yanqiu;YANG Jun(Department of Obstetrics and Gynecology,Chongqing Health Center for Women and Children(Women and Children’s Hospital of Chongqing Medical University),Chongqing,401147,China;Department of Sleep&Psychology,Chongqing Health Center for Women and Children(Women and Children’s Hospital of Chongqing Medical University),Chongqing,401147,China)
出处
《陆军军医大学学报》
CAS
CSCD
北大核心
2024年第6期618-622,共5页
Journal of Army Medical University
基金
重庆市妇幼保健院院级科研课题面上项目(2020YJMS04、2020YJMS05)
国家临床重点专科建设项目(妇产科)
重庆医科大学未来医学青年创新团队支持计划(W0181)
重庆市科卫联合重点项目(2019ZDXM051)。
关键词
人乳头瘤病毒
认知行为疗法
宫颈
转归
human papillomavirus
cognitive behavioral therapy
cervix
reversion
