摘要
目的分析研究罹患咽喉反流性疾病患者予以奥美拉唑、莫沙必利的应用价值。方法选取2018.12-2021.12区间本院收治80例咽喉反流性疾病患者作为主体展开对照分析,依据治疗方式差异性展开规范分组,记对照组(n=40)、观察组(n=40),前组予以常规治疗,后组奥美拉唑联合莫沙必利,统计两组各项指标(治疗效果评估值、不良反应评估值、生活质量测评值、临床症状改善时间测评值)展开细致观测并实施对比分析。结果观察组治疗有效率占比高于对照组,P<0.05。观察组不良反应占比低于对照组,但无显著差异,P>0.05。干预前生活质量无显著差异,P>0.05;干预后观察组高于对照组,P<0.05。观察组症状消失时间测评值低于对照组,P<0.05。结论在咽喉反流性疾病患者治疗期间通过予以奥美拉唑药物、莫沙必利药物结合治疗,具有缩短症状改善时间、提高生活质量、减少不良反应的效果,很大程度上提高了治疗水平,在临床中具有借鉴及应用推广价值。
Objective To analyze and study the application value of omeprazole and mosapride in patients with laryngopharyngeal reflux disease.Methods A total of 80 patients with laryngopharyngeal reflux disease from December 2018 to December 2021 were selected and divided into control group(N=40)and observation group(N=40),the former group was treated with conventional therapy,while the latter group was treated with omeprazole combined with mosapride therapy,all the indexes(therapeutic effect,adverse reaction,quality of life and time of clinical symptom improvement)in the two groups were observed and analyzed.Results The effective rate of the observation group was higher than that of the control group(p<0.05).The proportion of adverse reactions in the observation group was lower than that in the control group,but there was no significant difference(P>0.05).There was no significant difference in quality of life before intervention(P>0.05),but it was higher in the observation group than in the control group after intervention(p<0.05).The time of symptom disappearance in the observation group was lower than that in the control group(p<0.05).Conclusion The combination of omeprazole and Mosapride can shorten the time of symptom improvement,improve the quality of life and reduce the adverse reactions in the treatment of patients with pharyngeal and laryngeal reflux disease,to a great extent,it improves the level of treatment and has the value of reference and application in clinical practice.
作者
韩吉作
Han Jizuo(Rizhuang Central Hospital of Laixi City,Qingdao,Shandong,266000,China)
出处
《中国医学文摘（耳鼻咽喉科学）》
2024年第1期99-101,共3页
Chinese Medical Digest(Otorhinolaryngology)
