摘要
目的:分析医院2018年—2022年住院患者抗菌药物使用强度(antimicrobial use density,AUD)的变化趋势,为下一步抗菌药物管理制度的制定提供参考。方法:通过医院信息系统采集2018年—2022年张家港澳洋医院住院患者的抗菌药物使用数据,分析5年间医院AUD的整体变化情况,以及不同剂型、不同级别、不同种类抗菌药物AUD的变化。结果:5年间,医院住院患者的AUD从60.34降至48.04,其中注射剂型抗菌药物的AUD占比始终较高(94.71%~95.74%);限制级抗菌药物的AUD占比从2018年的70.45%降至2022年的42.42%,而非限制级抗菌药物的AUD占比从2018年的26.87%升至2022年的52.17%;在各药物种类中,5年间头孢菌素类药物的AUD始终最高,但呈缓慢下降趋势(从2018年的37.26降至2022年的29.54),其中又以第3代头孢菌素的AUD为最高。结论:5年间,医院住院患者的抗菌药物使用日趋规范,抗菌药物规范管理取得一定成效,但仍存在使用品种较为集中的不合理现象,医院行政部门应继续加强管理,以提高医院的抗菌药物合理使用水平。
Objective:To analyze the trend of changes in antimicrobial use density(AUD) among inpatients in a hospital from 2018 to 2022,and to provide reference for the subsequent formulation of antimicrobial drug management systems.Methods:The data of use of antibacterial drugs were collected from inpatients in Zhangjiagang Aoyang Hospital from 2018 to 2022 through the hospital information system,and the overall changes in AUD in the hospital over the past five years,as well as the changes in AUD of different dosage forms,grades,and types of antibacterial drugs were analyzed.Results:Over the past five years,AUD of inpatients in the hospital decreased from 60.34 to 48.04,with a consistently high proportion of AUD for injectable antibacterial drugs(94.71% to 95.74%).The proportion of AUD for restricted grade antibacterial drugs decreased from 70.45% in 2018 to 42.42% in 2022,while the proportion of AUD for non-restricted grade antibacterial drugs increased from 26.87% in 2018 to 52.17% in 2022.Among various types of drugs,the AUD of cephalosporin drugs remained the highest over the past five years,but showed a slow downward trend(from 37.26 in2018 to 29.54 in 2022),with the AUD of third-generation cephalosporins as the highest.Conclusion:Over the past five years,antibacterial drugs for the hospital inpatients have been increasingly normatively used,and the normative management of antibacterial drugs has achieved certain results.However,there is still an unreasonable phenomenon that the varieties used are relatively concentrated.The administrative department of the hospital should continue to strengthen management to improve the level of rational use of antibacterial drugs in the hospital.
作者
陆兵
蔡燕
杨慧
刘栋
曾雅溪
张曼
LU Bing;CAI Yan;YANG Hui;LIU Dong;ZENG Ya-xi;ZHANG Man(Zhangjiagang Aoyang Hospital,Zhangjiagang Jiangsu 215600,China)
出处
《抗感染药学》
2023年第11期1141-1146,共6页
Anti-infection Pharmacy
关键词
住院患者
抗菌药物
抗菌药物使用强度
合理用药
inpatients
antibacterial drug
antimicrobial use density
rational drug use
