摘要
目的:分析医院神经外科手术患者围术期抗菌药物的合理用药情况,为临床手术患者的抗菌药物合理使用提供参考。方法:选取2020年1月—2023年1月萍乡市第二人民医院神经外科收治的254例手术患者作为研究对象,统计患者围术期预防用抗菌药物的用药品种、用药时机、用药疗程等信息,并依据相关规范分析患者围术期抗菌药物的合理用药状况。结果:254例手术患者中有141例围术期预防性使用了抗菌药物,使用率为55.51%;其中,使用最多的药物为头孢唑林(71例,占50.35%)和头孢呋辛(44例,占31.21%),用药时机主要为术前0.5~1 h(122例,占86.52%),用药疗程多为≤24 h(98例,占69.50%);合理用药点评结果显示,患者的抗菌药物使用存在较多的不合理情况,其中主要为用药疗程过长(43例,不合理率为30.50%),其次为药物品种选择不当(26例,不合理率为18.45%)和给药时机不当(19例,不合理率为13.48%)。结论:医院神经外科手术患者围术期抗菌药物的使用存在较多的不合理现象,主要体现在用药疗程、品种选择和给药时机方面,医院应加强对临床抗菌药物使用的管理,以提高临床的合理用药水平。
Objective:To analyze the rational use of antibacterial drugs in neurosurgical patients during perioperative period in a hospital,and to provide reference for the rational use of antibacterial drugs in clinical surgical patients.Methods:254 surgical patients admitted to Neurosurgery Department of Pingxiang No.2 People's Hospital from January2020 to January 2023 were selected as the research subjects.Information on varieties,timing,and course of prophylactic antibacterial drugs in patients during perioperative period was collected,and the rational use of antibacterial drugs in patients during perioperative period was analyzed according to relevant standards.Results:Among 254 surgical patients,141 had prophylactic use of antibacterial drugs during perioperative period,with a usage rate of 55.51%;among the drugs,cefazolin(71 cases,50.35%) and cefuroxime(44 cases,31.21%) were most commonly used.The timing of medication was mainly 0.5-1 hour before surgery(122 cases,86.52%),and the course of medication was mostly less than or equal to 24 hours(98 cases,69.50%).The results of rational drug use reviews showed that there were many unreasonable situations in use of antibacterial drugs by patients,mainly in overlong course of medication(43 cases,with the irrational use rate of 30.50%),followed by improper selection of drug varieties(26 cases,with the irrational use rate of 18.45%)and improper timing of administration(19 cases,with the irrational use rate of 13.48%).Conclusion:There is much irrational use of antibacterial drugs in neurosurgical patients during perioperative period in the hospital,mainly in course of medication,selection of varieties,and timing of administration.The Hospital should strengthen the management of clinical antibacterial drug use to improve the level of rational drug use in clinical practice.
作者
何佳佳
李金亮
易宇光
吴俊波
HE Jia-jia;LI Jin-liang;YI Yu-guang;WU Jun-bo(Pingxiang No.2 People's Hospital,Pingxiang Jiangxi 337000,China)
出处
《抗感染药学》
2023年第11期1146-1149,共4页
Anti-infection Pharmacy
关键词
神经外科
手术患者
围术期
抗菌药物
合理用药
neurosurgery
surgical patient
perioperative period
antibacterial drug
rational drug use
