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经典名方异功散的历史沿革及临床应用考证 被引量:2

Historical evolution and clinical application of classical prescription Yigongsan
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摘要 异功散出自宋代钱乙的《小儿药证直诀》,收录于2022年国家中医药管理局发布的《古代经典名方目录(第二批儿科部分)》。本文通过系统梳理古籍文献和现代文献,对异功散的方剂历史源流、组成、剂量、炮制、煎服法和主治功效等进行考证分析。结果可得,异功散由人参、茯苓、白术、陈皮、甘草5味药组成,其中茯苓需去皮,白术采用土炒法,甘草采用蜜炙法,人参和陈皮用生品;根据古今剂量折算,异功散煎服时须将各药材研为细末,各称取1.6 g,加水300 mL、生姜5片、枣2个,共同煎煮至210 mL,饭前温服。异功散在古籍中记载的主治病证为呕吐泄泻、脾胃虚冷、胸脘痞闷、不思饮食等,在现代广泛应用于免疫系统、呼吸系统、血液系统等,涉及小儿厌食症、哮喘、贫血、肿瘤等多种疾病。 Yigongsan,derived from QIAN Yi’s Key to Therapeutics of Children’s Diseases in the Song Dynasty,is a classic pediatric prescription that is included in the Catalogue of Ancient Classic Prescriptions(the Second Batch of Pediatrics)released by the National Administration of Traditional Chinese Medicine in 2022.This paper verifies and analyzes the historical origin,composition,dosage,processing,decoction method and efficacy of Yigongsan by systematically combing ancient books and modern documents.As a result,Yigongsan is composed of five herbs:Panax ginseng,Poria cocos,Atractylodes macrocephala,Citrus reticulata and Glycyrrhiza uralensis,of which P.cocos should be peeled,A.macrocephala is fried with soil,G.uralensis is roasted with honey while P.ginseng and C.reticulata are raw products.According to the dosage of ancient and modern times,each medicinal herb must be ground into fine powder,1.6 g for each,added with 300 mL of water,5 pieces of Zingiber officinale,and 2 Ziziphus jujuba,decocted together to 210 mL,and taken before meals.In ancient books,Yigongsan is used to treat vomiting,diarrhea,spleen and stomach deficiency,chest and abdominal distension,and lack of appetite,etc.Modern research showed that Yigongsan could also be used in the diseases of immune system,respiratory system,blood system,etc.,involving infantile anorexia,asthma,anemia,tumors and so on.
作者 陈娜 郭景仙 褚燕琦 贡磊磊 姜新海 胡晓 张兰 CHEN Na;GUO Jingxian;CHU Yanqi;GONG Leilei;JIANG Xinhai;HU Xiao;ZHANG Lan(Dept.of Pharmacy,Xuanwu Hospital of Capital Medical University,Beijing 100053,China;Dept.of Pharmacy,Beijing Obstetrics and Gynecology Hospital Affiliated to Capital Medical University,Beijing 100026,China)
出处 《中国药房》 CAS 北大核心 2024年第1期119-123,共5页 China Pharmacy
基金 国家自然科学基金项目(No.82274611) 北京市医院管理中心“登峰”人才培养计划项目(No.DFL20190803)。
关键词 经典名方 异功散 文献考证 功效 classical prescription Yigongsan literature research efficacy
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