摘要
【目的】观察电针颈夹脊穴治疗急性期神经根型颈椎病的临床疗效。【方法】将124例急性期神经根型颈椎病患者随机分为对照组和观察组,每组各62例。对照组给予西药常规治疗。观察组在对照组治疗的基础上,给予电针颈夹脊穴治疗。连续治疗6周。治疗6周后,评价2组临床疗效,观察2组患者治疗前后颈椎生理曲度C2~7Cobb角的变化情况,以及麦吉尔疼痛问卷简表(SF-MPQ)评分、血清疼痛因子P物质(SP)、前列腺素E2(PGE2)水平的变化情况。比较2组患者治疗前后白细胞介素(IL)-6、IL-1β、肿瘤坏死因子α(TNF-α)、核因子-κB(NF-κB)水平的变化情况。并进行随访,统计复发率。【结果】(1)治疗后,2组患者颈椎生理曲度C2~7Cobb角均明显改善(P<0.05),且观察组在改善颈椎生理曲度C2~7Cobb角方面明显优于对照组,差异有统计学意义(P<0.05)。(2)治疗后,2组患者的颈椎疼痛SF-MPQ评分、SP、PGE2水平均明显改善(P<0.05),且观察组在改善颈椎疼痛SF-MPQ评分、SP、PGE2水平方面明显优于对照组,差异有统计学意义(P<0.05)。(3)治疗后,2组患者的IL-6、IL-1β、TNF-α、NF-κB水平明显改善(P<0.05),且观察组在改善IL-6、IL-1β、TNF-α、NF-κB水平方面明显优于对照组,差异有统计学意义(P<0.05)。(4)观察组总有效率为95.16%(59/62),对照组为80.65%(50/62)。观察组疗效优于对照组,差异有统计学意义(P<0.05)。(5)观察组患者症状复发率为5.71%(2/35),对照组为29.63%(8/27)。观察组患者症状复发率低于对照组,差异有统计学意义(P<0.05)。【结论】电针颈夹脊穴治疗急性期神经根型颈椎病,可显著缓解患者的疼痛症状,改变异常颈椎生理曲度,并减轻炎症反应,降低症状复发风险,疗效显著。
Objective To observe the clinical efficacy of applying electro-acupuncture at cervical Jiaji(EX-B2)point in the treatment of acute cervical spondylotic radiculopathy.Methods A total of 124 patients with acute cervical spondylotic radiculopathy were randomly divided into the control group and the observation group,with 62 cases in each group.The control group was given conventional treatment with western medicine.The observation group was given electro-acupuncture at cervical Jiaji point on the basis of the treatment of the control group.Both groups were treated for 6 consecutive weeks.After 6 weeks of treatment,the clinical efficacy of the two groups was evaluated,and the changes in the cervical physiological curvature C2-7Cobb angle of the two groups were observed before and after the treatment,as well as the changes in the score of the Short Form McGill Pain Questionnaire(SF-MPQ),the level of serum pain factor P substance(SP),and the level of prostaglandin E2(PGE2).Changes in interleukin(IL)-6,IL-1β,tumour necrosis factor-α(TNF-α),and nuclear factor-κB(NF-κB)levels were compared before and after treatment between the two groups.And follow-up was performed to calculate the recurrence rate.Results(1)After treatment,the cervical physiological curvature C2-7Cobb angle of patients in the two groups were significantly improved(P<0.05),and the observation group was significantly superior to the control group in improving the cervical physiological curvature C2-7Cobb angle,and the difference was statistically significant(P<0.05).(2)After treatment,the cervical spine pain SF-MPQ scores,SP,and PGE2 levels of patients in the two groups were significantly improved(P<0.05),and the observation group was significantly superior to the control group in improving the cervical spine pain SF-MPQ scores,SP,and PGE2 levels,and the differences were statistically significant(P<0.05).(3)After treatment,the levels of IL-6,IL-1β,TNF-α,and NF-κB of patients in the two groups were significantly improved(P<0.05),and the observation
作者
郭佳坤
程凯
朱晓晨
龚立冬
武晋廷
李嘉怡
GUO Jia-Kun;CHENG Kai;ZHU Xiao-Chen;GONG Li-Dong;WU Jin-Ting;LI Jia-Yi(School of Acupuncture,Moxibustion and Rehabilitation,Beijing University of Chinese Medicine,Beijing 100029,China;Tsinghua University Yuquan Hospital,Beijing 100049,China;Dongfang Hospital Beijing University of Chinese Medicine,Beijing 100078,China;Yangzhuang Community Health Service Centre,Beijing 100043,China)
出处
《广州中医药大学学报》
CAS
2024年第2期373-379,共7页
Journal of Guangzhou University of Traditional Chinese Medicine
基金
北京市卫生科技发展专项基金资助项目(编号:2019-3-217)。
关键词
电针
颈夹脊穴
急性期神经根型颈椎病
颈椎生理曲度
白细胞介素6
临床观察
electro-acupuncture
cervical Jiaji point
acute cervical spondylotic radiculopathy
cervical physiological curvature
interleukin-6(IL-6)
clinical observation
