可降解锌合金骨植入材料的研究进展

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摘要由于创伤、感染和骨肿瘤切除以及先天性疾病等因素导致的骨缺损患者逐年增多,部分骨质丧失造成的骨不连、骨萎缩甚至畸形等并发症,是临床常见且较难治疗的疾病之一。目前对大段骨缺损的治疗主要是应用来源有限的自体骨或异体骨,以及应用不锈钢、钛合金等骨替代材料进行移植,以填充骨缺损并促进其修复和重建,虽然金属填充材料的力学性能较好,但在人体内不能降解,长时间滞留体内所产生的金属离子对周围组织造成一定的损害,因为其弹性模量远大于人骨骼的弹性模量,所以会产生应力遮挡效应等问题。

作者曹向昱车浩东李亚庚田华

机构地区北京大学第三医院骨科北京科技大学材料科学与工程学院

出处《实用骨科杂志》 2024年第1期54-58,共5页 Journal of Practical Orthopaedics

关键词骨植入材料异体骨先天性疾病应力遮挡效应骨不连骨缺损自体骨锌合金

分类号 R318.08 [医药卫生—生物医学工程]

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可降解锌合金骨植入材料的研究进展

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二级参考文献11

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