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三维创伤外固定架系统联合皮瓣修复治疗胫腓骨开放性骨折合并软组织缺损的效果及对创伤愈合情况、炎性因子水平的影响

Effect of three-dimensional trauma external fixator system combined with flap repair in the treatment of open fracture of tibia and fibula with soft tissue defect and its influences on wound healing and inflammatory factors levels
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摘要 目的探讨三维创伤外固定架系统联合皮瓣修复治疗胫腓骨开放性骨折合并软组织缺损的效果。方法选取2019年1月至2022年1月收治的120例胫腓骨开放性骨折合并软组织缺损患者作为研究对象,以治疗方法的差异性将其分为对照组和观察组,各60例。对照组采用常规固定联合皮瓣修复治疗,观察组采用三维创伤外固定架系统联合皮瓣修复治疗。比较两组的治疗效果。结果观察组的治疗总有效率高于对照组(P<0.05)。术后1个月,观察组的Lane-Sandhu X线评分高于对照组(P<0.05)。术后1 d,观察组的C反应蛋白(CRP)、白细胞介素-6(IL-6)、肿瘤坏死因子-α(TNF-α)水平低于对照组(P<0.05)。术后3个月,观察组的踝关节Kofoed功能评分高于对照组(P<0.05)。结论三维创伤外固定架系统联合皮瓣修复治疗胫腓骨开放性骨折合并软组织缺损的效果显著,可促进患者创伤愈合,降低炎性因子水平,也有助于关节功能的快速恢复。 Objective To investigate the effect of three-dimensional trauma external fixator system combined with flap repair in the treatment of open fracture of tibia and fibula with soft tissue defect.Methods A total of 120 patients with open fracture of tibia and fibula with soft tissue defect admitted from January 2019 to January 2022 were selected as the research objects,and the patients were divided into control group and observation group according to the difference of treatment methods,with 60 cases in each group.The control group was treated with conventional fixation combined with flap repair,and the observation group was treated with three-dimensional trauma external fixator system combined with flap repair.The therapeutic effects of the two groups were compared.Results The total effective rate of treatment in the observation group was higher than that in the control group(P<0.05).At 1 month after operation,the Lane-Sandhu X-ray score of the observation group was higher than that of the control group(P<0.05).At 1 d after operation,the levels of C-reactive protein(CRP),interleukin-6(IL-6)and tumor necrosis factor-α(TNF-α)in the observation group were lower than those in the control group(P<0.05).At 3 months after operation,the ankle Kofoed function score of the observation group was higher than that of the control group(P<0.05).Conclusion Three-dimensional trauma external fixator system combined with flap repair is effective in the treatment of open fracture of tibia and fibula with soft tissue defect.It can promote wound healing of patients,reduce the levels of inflammatory factors,and also contribute to the rapid recovery of joint function.
作者 醋晓川 刘海军 侯晓进 CU Xiaochuan;LIU Haijun;HOU Xiaojin(Baoji Central Hospital,Baoji 721000;Xianyang Hospital of Yan'an University,Xianyang 712000,China)
出处 《临床医学研究与实践》 2024年第1期77-80,共4页 Clinical Research and Practice
基金 延安大学咸阳医院2020年度院内科学研究基金项目(No.2020ZX050)。
关键词 三维创伤外固定架系统 皮瓣修复 胫腓骨开放性骨折 软组织缺损 炎性因子 three-dimensional trauma external fixator system flap repair open fracture of tibia and fibula soft tissue defect inflammatory factor
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