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应变式弹性成像联合超声造影在甲状腺滤泡性肿瘤患者诊断中的应用价值研究

The Application Value of Strain Gauge Elastography Combined with Contrast-enhanced Ultrasound in the Diagnosis of Thyroid Follicular Tumors
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摘要 目的分析应变式弹性成像与超声造影(CEUS)联合诊断甲状腺滤泡性肿瘤患者的价值。方法选取2019年6月至2021年3月于我院诊治的101例甲状腺滤泡性肿瘤患者作为研究对象,所有患者均经术后病理证实,其中59例为滤泡性腺瘤患者,为滤泡性腺瘤组;42例为滤泡癌患者,为滤泡癌组,分析应变式弹性成像、CEUS诊断两组患者的影像学特征和诊断效能。结果滤泡性腺瘤和滤泡癌患者的弹性评分、CEUS评分构成比差异有统计学意义(P<0.05)。分析受试者工作特征(ROC)曲线,弹性成像诊断甲状腺滤泡性肿瘤的最佳诊断点为2分,AUC为0.859,特异度为57.83%,灵敏度为94.71%。CEUS诊断甲状腺滤泡性肿瘤的最佳诊断点为2分,AUC为0.873,特异度为83.42%,灵敏度为72.15%。联合诊断时AUC最高为0.945,差异有统计学意义(P<0.05),特异度为96.18%,灵敏度为89.25%。结论应变式弹性成像与CEUS诊断鉴别甲状腺滤泡性肿瘤良恶性程度,其诊断效能高于应变式弹性成像和超声造影单独诊断,可获得较高的诊断准确性。 Objective Analyze the value of combining strain gauge elastography with contrast-enhanced ultrasound(CEUS)in the diagnosis of patients with thyroid follicular tumors.Methods 101 patients with thyroid follicular tumors who were diagnosed and treated in our hospital from June 2019 to March 2021 were selected as the research subjects.All patients were confirmed by postoperative pathology,of which 59 were follicular adenoma patients,belonging to the follicular adenoma group;42 patients with follicular carcinoma were included in the follicular carcinoma group.The imaging characteristics and diagnostic efficacy of strain gauge elastography and CEUS diagnosis were analyzed in both groups.Results There was a statistically significant difference in the composition of elastic score and CEUS score between patients with follicular adenoma and follicular cancer(P<0.05).Analyzing the receiver operating characteristic(ROC)curve,the optimal diagnostic point for thyroid follicular tumors using elastography is 2 points,with an AUC of 0.859,a specificity of 57.83%,and a sensitivity of 94.71%.The optimal diagnostic point for thyroid follicular tumors using CEUS is 2 points,with an AUC of 0.873,a specificity of 83.42%,and a sensitivity of 72.15%.The highest AUC during combined diagnosis was 0.945,with a statistically significant difference(P<0.05),a specificity of 96.18%,and a sensitivity of 89.25%.Conclusion Strain mode elastography and CEUS diagnosis differentiate the degree of benign and malignant thyroid follicular tumors,and their diagnostic efficiency is higher than that of strain mode elastography and contrast-enhanced ultrasound alone,which can achieve high diagnostic accuracy.
作者 姚晶晶 时贵阁 Yao Jing-jing;Shi Gui-ge(Ultrasound Diagnosis Department of Pingmei Shenma Group General Hospital,Pingdingshan 467000,Henan Province,China)
出处 《罕少疾病杂志》 2023年第11期34-36,共3页 Journal of Rare and Uncommon Diseases
关键词 应变式弹性成像 超声造影 甲状腺滤泡性肿瘤 诊断价值 Train Type Elastic Imaging Contrast-enhanced Ultrasound Thyroid Follicular Tumors Diagnostic Value
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