摘要
目的 研究近视合并不同程度散光患者应用波前像差引导飞秒激光辅助制瓣的准分子激光原位角膜磨镶术(FS-LASIK)治疗的临床疗效。方法 选择2018年6月至2021年3月咸阳爱尔眼科医院收治的131例262眼近视合并散光患者进行研究,按照不同程度散光分组,其中低散光组61例122眼,中散光组53例106眼,高散光组17例34眼,所有患者均采用FS-LASIK治疗。比较三组患者术前最佳矫正视力(术前BCVA)及术后3个月的裸眼视力(UCVA)、有效性指数、残余屈光度;比较三组患者手术前后的角膜高阶像差(包含总高阶像差、球差、垂直彗差、水平彗差、水平三叶草差、倾斜三叶草差)。结果 三组患者术前BCVA、术后3个月UCVA和有效性指数比较差异均无统计学意义(P>0.05);术后3个月,高散光组患者的残余屈光度为(-0.289±0.027) D,明显高于中散光组和低散光组的(-0.253±0.026) D、(-0.159±0.021) D,且中散光组残余屈光度明显高于低散光组,差异均有统计学意义(P<0.05);术后3个月,低散光组患者的总高阶像差、球差、垂直彗差分别为(0.635±0.221)μm、(0.412±0.158)μm、(-0.273±0.081)μm,明显高于术前的(0.399±0.121)μm、(0.223±0.095)μm、(-0.079±0.015)μm,差异均有统计学意义(P<0.05),而水平彗差、水平三叶草差、倾斜三叶草差与术前比较差异均无统计学意义(P>0.05);术后3个月,中散光组患者的总高阶像差、球差、垂直彗差分别为(0.647±0.212)μm、(0.385±0.056)μm、(-0.268±0.005)μm,明显高于术前的(0.398±0.113)μm、(0.221±0.063)μm、(-0.038±0.012)μm,差异均有统计学意义(P<0.05),而水平彗差、水平三叶草差、倾斜三叶草差与术前比较差异均无统计学意义(P>0.05);术后3个月,高散光组患者的总高阶像差、球差、垂直彗差分别为(0.650±0.132)μm、(0.275±0.082)μm、(-0.238±0.096)μm,明显高于术前的(0.398±0.092)μm、(0.208±0.061)μm、(-0.082±0.013)μm,差异均有统计学
Objective To investigate the clinical efficacy of wavefront aberration-guided femtosecond laser-as-sisted in situ keratomileusis(FS-LASIK)in patients with myopia with varying degrees of astigmatism.Methods A study was conducted on 131 patients with 262 eyes of myopia and astigmatism admitted to Xianyang Aier Eye Hospital from June 2018 to March 2021.They were grouped according to different degrees of astigmatism,including 61 patients with 122 eyes in the low astigmatism group,53 patients with 106 eyes in the medium astigmatism group,and 17 patients with 34 eyes in the high astigmatism group.All patients received FS-LASIK treatment.The best corrected visual acuity(BCVA)before surgery and the naked eye visual acuity(UCVA),efficacy index,and residual refractive index of three groups of patients at three months after surgery were compared.The corneal high-order aberrations(including total high-order aberrations,spherical aberrations,vertical coma,horizontal coma,horizontal clover aberration,and tilted clo-ver aberration)of the three groups of patients before and after surgery were compared.Results There was no statistically significant difference in BCVA before surgery,UCVA at 3 months after surgery,and efficacy index among the three groups(P>0.05).Three months after surgery,the residual refractive index of patients in the high astigmatism group was(-0.289±0.027)D,which was significantly higher than(-0.253±0.026)D in the medium and(-0.159±0.021)D in low astigma-tism groups,and the residual refractive index in the medium astigmatism group was significantly higher than that in the low astigmatism group,with statistically significant differences(P<0.05).Three months after surgery,the total high-or-der aberration,spherical aberration,and vertical coma of the low astigmatism group were(0.635±0.221)μm,(0.412±0.158)μm,and(-0.273±0.081)μm,which were significantly higher than(0.399±0.121)μm,(0.223±0.095)μm,and(-0.079±0.015)μm before surgery,with statistically significant differences(P<0.05),but there was no sta
作者
李婧媛
李淑琴
万婧
LI Jing-yuan;LI Shu-qin;WAN Jing(Department of Ocular Fundus Disease,Xianyang Aier Eye Hospital,Xianyang 712000,Shaanxi,CHINA;Department of Ophthalmology,Affiliated Hospital of Gansu Medical College,Pingliang 744000,Gansu,CHINA)
出处
《海南医学》
CAS
2023年第20期2954-2958,共5页
Hainan Medical Journal
基金
爱尔眼科集团自由探索计划项目(编号:AF1909D4、AF2009D8)。