摘要
目的通过心脏磁共振(CMR)评估中国健康成人左心房(LA)心肌应变(MS)及应变率(SR)特定于性别及年龄的正常值。方法回顾性纳入110例健康成人[(45.65±12.77)岁,男性76例],所有人均行3.0 T CMR检查,并按照性别及年龄分层。使用CMR评估LA整体纵向应变(GLS)、GLS SR、整体圆周应变(GCS)。其中GLS分为储存期(reservoir)、管道期(conduit)、泵血期(booster)3个阶段。结果与男性相比,女性LA GLS reservoir、GLS conduit、GCS及SR reservoir显著较大(P<0.05)。不同年龄段之间LA GLS reservoir、SR reservoir及GLS conduit、SR conduit差异有统计学意义(所有P<0.05),且随着年龄增长逐渐下降。女性的年龄与LA GLS conduit、SR conduit呈显著负相关(P<0.001),与GLS booster显著正相关(P=0.034)。男性的年龄与LA GLS(reservoir、conduit)及SR(reservoir、conduit)均呈显著负相关(P≤0.001)。结论CMR可用于量化LA MS及SR,与年龄和性别相关的LA MS及SR差异的存在表明,有必要为个体群体建立特定的正常值。
Objective The aim of this study was to assess sex⁃and age⁃specific normal values of left atrium(LA)myo⁃cardial strain(MS)and strain rate(SR)in healthy adults in China by cardiac magnetic resonance(CMR).Methods 110 healthy adults(45.65±12.77,76 males)were retrospectively included,all of whom underwent 3.0T CMR and were stratified according to gender and age.LA global longitudinal strain(GLS),GLS SR,and global circumferential strain(GCS)were assessed using CMR.The GLS is divided into three stages:Reservoir,Conduit and Booster.Results LA GLS Reservoir,GLS Conduit,GCS and SR Reservoir were significantly greater in females compared to males(P<0.05).Differ⁃ences in LA GLS Reservoir,SR Reservoir and GLS Conduit and SR Conduit between age groups were statistically significant(all P<0.05)and gradually decreased with increasing age.Among females,age was significantly negatively correlated with LA GLS Conduit,SR Conduit(P<0.001),significantly positively correlated with GLS Booster(P=0.034)and not signif⁃icantly correlated with GLS Reservoir(P=0.070).In the male population,a significant negative correlation(P≤0.001)could be found between age and both LA GLS(Reservoir,Conduit)and SR(Reservoir,Conduit).Conclusion CMR is feasible and reproducible for quantifying LA MS and SR and determining left atrial phase function.The presence of age⁃and sex⁃related differences in LA MS and SR suggests the need to establish specific normal values for individual groups.
作者
田迪
张靖雨
熊梓琦
胡帅
宋清伟
李智勇
TIAN Di;ZHANG Jingyu;XIONG Ziqi(Department of Radiology,The First Affiliated Hospital of Dalian Medical University,Dalian,Liaoning Province 116011,P.R.China)
出处
《临床放射学杂志》
北大核心
2023年第9期1453-1458,共6页
Journal of Clinical Radiology
基金
辽宁省教育厅科研基金项目(编号:L2016021)。
关键词
心脏磁共振
左心房
心肌应变
应变率
健康成人
Cardiac magnetic resonance
Left atrium
Myocardial strain
Strain rate
Healthy adults
