摘要
心外膜脂肪组织(epicardial adipose tissue, EAT)位于心肌和脏层心包之间,具有代谢、产热、独特的转录、分泌谱和可测量性等特点,与多种心血管相关疾病存在密切的关系,其可能是潜在的心血管疾病治疗靶点,近年来得到大量的研究。影像学是检测和评估EAT最主要的手段,其中心脏磁共振(cardiac magnetic resonance, CMR)成像具有高空间分辨率、无辐射、良好组织对比度等有点,目前被认为是EAT定量评估主要方法。本文就EAT的CMR成像原理、成像序列、测量软件及研究进展作一综述。
Epicardial adipose tissue(EAT) is located between the myocardium and visceral pericardium. EAT has characteristics of metabolism, calorihism, unique transcription, secretion profile and calcalability. It has been reported that EAT may be a potential therapeutic target for cardiovascular diseases. Imaging is the most important method to detect and evaluate EAT, among which cardiac magnetic resonance(CMR) has high spatial resolution, no radiation damage and good tissue contrast, and is currently considered as the main method for quantitative evaluation of EAT. In this review, we submitted the CMR imaging principle, sequences, measurement software and research progress of EAT.
作者
马延
王晶鑫
王斌
罗松
蔡军
MA Yan;WANG Jingxin;WANG Bin;LUO Song;CAI Jun(Department of Diagnostic Radiology,Jinling Hospital,Medical School of Nanjing University,Nanjing 210002,China)
出处
《磁共振成像》
CAS
CSCD
北大核心
2022年第8期142-145,共4页
Chinese Journal of Magnetic Resonance Imaging
基金
国家自然科学基金(编号:81601486)。
关键词
心外膜脂肪组织
心脏磁共振成像
左心室舒张功能障碍
epicardial adipose tissue
cardiac magnetic resonance imaging
left ventricular diastolic dysfunction
