摘要
目的分析足月新生儿早期重度缺氧缺血性脑病的颅脑磁共振表现,以提高早期诊断率。方法回顾性分析经临床确诊的7名足月儿早期重度缺氧缺血性脑病的临床及MR资料。结果7名足月儿早期重度缺氧缺血性脑病患儿DWI序列除脑室周围或皮层及皮层下区受累以外,均可见胼胝体受累;T1WI显示5例内囊后肢高信号减弱或消失,其中4例合并基底节区、脑干T1WI信号明显升高或T_(2)WI明显减低情况;2例出现广泛硬膜下血肿形成;SWI显示1例幕上皮层及皮层下多灶性出血。7例中有2例分别于23天、25天进行了短期复查,1例出现右侧顶叶大面积软化,1例出现幕上全脑白质软化。结论足月儿早期缺氧缺血性脑病,有其特征性表现,当出现胼胝体损伤时,要考虑到重度脑病的可能,另外中央脑质区如基底节及脑干T1WI升高或T_(2)WI减低信号,对于重度缺氧缺血性脑病的诊断有一定的提示作用。
Objective To analyze the brain MRI manifestations of early severe hypoxic-ischemic encephalopathy in full-term neonates,so as to improve the early diagnosis rate.Methods The clinical and MR data of 7 full-term infants with early severe hypoxic-ischemic encephalopathy were retrospectively analyzed.Results Seven full-term infants with early severe hypoxic-ischemic encephalopathy showed corpus callosum involvement except for periventricular or cortical and subcortical areas.T1WI showed that the high signal intensity of the posterior limb of the internal capsule was weakened or disappeared in 5 cases,and 4 cases were combined with significant increase of T1WI signal or decrease of T_(2)WI signal in the basal ganglia and brainstem.2 cases had extensive subdural hematoma formation;SWI showed 1 case of multifocal hemorrhage in the cortical and subcortical layers.Two of the seven cases underwent short term follow-up at 23 and 25 days,respectively.One case showed extensive right parietal lobe softening and one case showed supratentorial white matter softening.Conclusion Early hypoxic-ischemic encephalopathy in term infants has its own characteristic manifestations.When the corpus callosum injury occurs,the possibility of severe encephalopathy should be considered.In addition,the central brain regions such as basal ganglia and brainstem T1WI increased or T_(2)WI decreased signal,which has a certain role in the diagnosis of severe hypoxic-ischemic encephalopathy.
作者
罗震
温浦钲
刘志博
刘晶哲
LUO Zhen;WEN Pu-zheng;LIU Zhi-bo;LIU Jing-zhe(Department of Radiology,The First Hospital of Tsinghua University,Beijing 100016,China)
出处
《中国CT和MRI杂志》
2023年第10期30-32,共3页
Chinese Journal of CT and MRI
关键词
新生儿
缺氧缺血性脑病
功能成像
磁共振成像
Newborn
Hypoxic-ischemic Encephalopathy
Functional Imaging
Magnetic Resonance Imaging
