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桃红四物汤联合闭合复位外固定术治疗胫腓骨骨折疗效观察及对血液流变学、生活质量的影响 被引量:1

Clinical Study on the Curative Effect of Taohong Siwu Decoction Combined with Closed Reduction and External Fixation for the Treatment of Tibiofibular Fractures and Its Influence on Hemorheology and Quality of Life
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摘要 目的:观察桃红四物汤联合闭合复位外固定术治疗胫腓骨骨折的临床疗效。方法:选取124例胫腓骨骨折患者,按随机数字表法分为研究组和对照组各62例。对照组采用闭合复位外固定术治疗,研究组在对照组基础上加用桃红四物汤治疗。比较2组临床疗效及治疗前后疼痛视觉模拟评分法(VAS)评分、肢体肿胀程度、血液流变学指标水平、生活质量综合评定问卷(GQOLI-74)评分。结果:研究组总有效率为93.5%,对照组为82.3%,2组比较,差异有统计学意义(P<0.05)。治疗后,2组疼痛VAS评分、患肢周径差均较治疗前降低(P<0.05),且研究组上述2项指标均低于对照组(P<0.05)。治疗后,2组血沉、红细胞压积、全血黏度、血浆黏度水平均较治疗前降低(P<0.05),且研究组上述各项指标均低于对照组(P<0.05)。治疗后,2组GQOLI-74量表中躯体功能、心理功能、社会功能、生活状态等评分均较治疗前升高(P<0.05),且研究组上述各项评分均高于对照组(P<0.05)。结论:桃红四物汤联合闭合复位外固定术治疗胫腓骨骨折疗效显著,可有助于缓解疼痛,促进肿胀消退,改善血液流变学状态,提高患者生活质量。 Objective:To observe the clinical effect of the therapy of Taohong Siwu Decoction combined with closed reduction and external fixation on tibiofibular fractures.Methods:A total of 124 patients with traumatic limb closed fracture were selected and randomly divided into the study group and the control group,with 62 cases in each group.The control group was additionally treated with closed reduction and external fixation,and the study group was additionally treated with Taohong Siwu Decoction.The visual analogue scale(VAS)of pain score,degree of limb swelling,hemorheology indexes and Generic Quality of Life Inventory(GQOLI-74)were compared before and after treatment between the two groups.Results:After treatment,the total effective rate was 93.5%in the study group and 82.3%in the control group,the difference being significant(P<0.05).After treatment,the VAS pain score and limb circumference difference in both groups were lowe decreased when compared with those before treatment(P<0.05),and the above two indexs in the study group were lower than those in the control group(P<0.05).After treatment,the levels of erythrocyte sedimentation rate,hematocrit,whole blood viscosity and plasma viscosity in the two groups were all decreased when compared with those before treatment(P<0.05),and the above levels in the study group were lower than those in the control group(P<0.05).After treatment,the scores of physical function,psychological function,social function and living status of GQOLI-74 in the two groups were increased when compared with those before treatment(P<0.05),and the above scores in the study group were higher than those in the control group(P<0.05).Conclusion:The therapy of Taohong Siwu Decoction combined with closed reduction and external fixation has a significant curative effect on tibiofibular fracture,which can help to improve limb function and hemorheology status of patients and improve their quality of life.
作者 周崔崔 苑国峰 何宇 ZHOU Cuicui;YUAN Guofeng;HE Yu(Department of Orthopaedics of the Second Affiliated Hospital of Nanyang Medical College,Nanyang He'nan 473000,China)
出处 《新中医》 CAS 2023年第14期25-28,共4页 New Chinese Medicine
关键词 胫腓骨骨折 闭合复位 外固定术 桃红四物汤 血液流变学 生活质量综合评定量表 Tibiofibular fractures Closed reduction External fixation Taohong Siwu Decoction Hemorheology Generic Quality of Life Inventory
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