摘要
目的分析经胸超声心动图声学造影(cTTE)、经颅多普勒对比增强试验(c TCD)对隐源性缺血性脑卒中(CS)合并卵圆孔未闭(PFO)的诊断价值,以为临床合理选择诊断方式提供参考。方法以2019年1月至2020年12月我院收治的130例CS患者为研究组,以同期于我院进行体检的130例健康志愿者为对照组。两组均行cTTE、cTCD、经食管超声心动图(TEE)检查。比较两组的PFO检出情况;以TEE为金标准,比较cTTE、cTCD对研究组PFO的诊断效能。结果TEE检出PFO 76例,其中研究组58例,对照组18例;研究组的PFO检出率高于对照组,差异具有统计学意义(P<0.05)。cTTE对研究组PFO的诊断准确度、灵敏度、特异度分别为93.85%、89.66%、97.22%;cTCD对研究组PFO的诊断准确度、灵敏度、特异度分别为82.31%、70.69%、91.67%;cTTE对研究组PFO的诊断准确度、灵敏度高于cTCD,差异具有统计学意义(P<0.05);cTTE、cTCD对研究组PFO的诊断特异度比较,差异无统计学意义(P>0.05)。结论PFO在CS患者中具有较高的发病率,cTTE与c TCD均能够有效诊断PFO,但cTTE具有更高的准确度与灵敏度。
Objective To analyze the diagnostic value of contrast transthoracic echocardiography(cTTE)and contrast-enhanced transcranial Doppler(cTCD)in cryptogenic ischemic stroke(CS)complicated with patent foramen ovale(PFO),so as to provide references for clinical rational selection of diagnostic methods.Methods A total of 130 CS patients admitted in our hospital from January 2019 to December 2020 were selected as study group,and 130 healthy volunteers who came to our hospital for physical examination during the same period were selected as control group.Both groups were examined by cTTE,cTCD and transesophageal echocardiography(TEE).The detection of PFO in the two groups was compared;using TEE as the gold standard,the diagnostic efficacy of cTTE and cTCD for PFO in the study group were compared.Results Seventy-six cases of PFO were detected by TEE,including 58 cases in the study group and 18 cases in the control group;the detection rate of PFO in the study group was higher than that in the control group,and the difference was statistically significant(P<0.05).The diagnostic accuracy,sensitivity and specificity of cTTE for PFO in the study group were 93.85%,89.66%and 97.22%,respectively;the diagnostic accuracy,sensitivity and specificity of cTCD for PFO in the study group were 82.31%,70.69%and 91.67%,respectively;the diagnostic accuracy and sensitivity of cTTE for PFO in the study group were higher than those of cTCD,and the differences were statistically significant(P<0.05);there was no significant difference in the diagnostic specificity of cTTE and cTCD for PFO in the study group(P>0.05).Conclusion PFO has a high incidence in CS patients.Both cTTE and cTCD can effectively diagnose PFO,but cTTE has higher accuracy and sensitivity.
作者
张建
赵茸
ZHANG Jian;ZHAO Rong(No.2 Neurology Department,Yulin No.2 Hospital,Yulin 719000,China;No.1 Neurology Department,Yulin No.2 Hospital,Yulin 719000,China)
出处
《临床医学研究与实践》
2023年第23期97-100,共4页
Clinical Research and Practice
