摘要
目的研究梅毒确证阳性献血者的风险因素,指导献血者招募,规避高危人群,提高血液安全性。方法2021年9月—2022年8月,采用两种梅毒抗体酶免试剂,筛查献血者标本44514份,反应性标本经TPPA确证。以采血时间、采血地点、献血次数、献血者性别、年龄、婚姻状况、文化程度7项为预测风险因素,经单因素Logistic回归分析,差异有统计学意义的因素,再进行多因素Logistic回归分析,确定最终的独立风险因素。结果酶免检测共检出梅毒抗体反应性标本121份,经TPPA确证阳性64份。剔除信息缺失者,共44505名献血者,纳入分析。经Logistic回归分析,在采血地点、献血次数、年龄、文化程度方面,差异有统计学意义。结论基于本市献血者梅毒阳性风险因素分析结果,应加强采血地点为献血屋的献血者征询,高危人群特征为50岁以上,初中及以下文化程度的初次献血者。
Objective To study the risk factors of blood donors confirmed to be positive for syphilis,so as to avoid high-risk groups,guide the recruitment of blood donors and improve blood safety.Methods From September 2021 to August 2022,44514 blood samples were screened using two enzyme-linked immunosorbent reagents for syphilis,and the reactive samples were confirmed by TPPA.Blood collection time,blood collection location,blood donation numbers,gender,age,marital status and educational level of blood donors were taken as the prediction risk factors,and factors with statistically significant differences by univariate Logistic regression analysis were further analyzed using multivariate factor Logistic regression analysis to determine the final independent risk factors.Results A total of 121 syphilis antibody reactive samples were detected by enzyme-linked immunosorbent assay,and 64 were confirmed positive by TPPA.Excluding those with incomplete information,a total of 44505 blood donors were included in the analysis.Logistic regression analysis showed that there were statistically significant differences in blood collection location,blood donation numbers,age and education level.Conclusion Based on the analysis results of risk factors of syphilis positive blood donors in Wuhu,it is necessary to strengthen the consultation of blood donors in blood donation sites.The high-risk groups are first-time blood donors over 50 years old,with education level of junior high school or below.
作者
黄慧
汪媛
杨旭
杨君
田园芳
袁松
潘安杰
HUANG Hui;WANG Yuan;YANG Xu;YANG Jun;TIAN Yuanfang;YUAN Song;PAN Anjie(Wuhu Blood Center,Wuhu 241000,China)
出处
《中国输血杂志》
CAS
2023年第7期590-593,共4页
Chinese Journal of Blood Transfusion
基金
芜湖市“十四五”医学重点培育输血技术专科。
