摘要
目的探讨抗米勒管激素(AMH)联合体重指数(BMI)检测在年龄≤35岁不孕症女性夫精人工授精(AIH)妊娠结局中的预测价值。方法回顾性分析2018年1月至2021年12月安徽省马鞍山市妇幼保健院接受AIH治疗且年龄≤35岁的261例不孕症女性(449个周期)。根据临床妊娠结局分为妊娠组(77个周期)和未妊娠组(372个周期)。比较两组一般资料、血清促卵泡成熟激素(FSH)、黄体生成素(LH)、催乳素(PRL)、雌二醇(E_(2))、孕酮(P)、睾酮(T)及AMH水平;受试者操作特征曲线分析AMH、BMI对AIH妊娠结局的预测价值。结果妊娠组BMI低于未妊娠组,AMH高于未妊娠组(P<0.05)。两组FSH、E_(2)、P、PRL、LH、T比较,差异无统计学意义(P>0.05)。AHM、BMI联合预测AIH妊娠结局的曲线下面积高于AMH、BMI单独预测(P<0.05)。结论AMH联合BMI检测对年龄≤35岁不孕症女性AIH妊娠结局具有一定的预测价值。
Objective To investigate the predictive value of anti-Mullerian hormone(AMH)combined with body mass index(BMI)in pregnancy outcome of infertile women aged≤35 years old after artificial insemination by husband(AIH).Methods A retrospective analysis was performed on 261 cases with infertile women aged≤35 years old(449 cycles)who received AIH treatment in Maanshan Maternal and Child Health Hospital,Anhui Province from January 2018 to December 2021.According to the clinical pregnancy outcome,they were divided into pregnant group(77 cycles)and non-pregnant group(372 cycles).The general information,follicle-stimulating hormone(FSH),luteinizing hormone(LH),prolactin(PRL),estradiol(E_(2)),progesterone(P),testosterone(T),and AMH levels of two groups were compared;the predictive value of AMH and BMI in AIH pregnancy outcome was analyzed by receiver operating characteristic curve.Results BMI of pregnant group was lower than that of non-pregnant group,and AMH was higher than that of non-pregnant group(P<0.05).There were no significant differences in FSH,E_(2),P,PRL,LH,and T between two groups(P>0.05).The area under the curve of AIH pregnancy outcome combined predicted by AHM and BMI was higher than that predicted by AMH and BMI alone(P<0.05).Conclusion AMH combined with BMI has a certain predictive value for AIH pregnancy outcome in infertile women aged≤35 years old.
作者
艾风连
张元宝
黄存
徐晓莲
潘维君
AI Fenglian;ZHANG Yuanbao;HUANG Cun;XU Xiaolian;PAN Weijun(Reproductive Center,Maanshan Maternal and Child Health Hospital,Anhui Province,Maanshan 243000,China)
出处
《中国医药导报》
CAS
2023年第21期117-120,共4页
China Medical Herald
基金
安徽省马鞍山市科技计划项目(YL-2020-03)。
关键词
宫腔内人工授精
抗苗勒管激素
体重指数
妊娠
Intrauterine insemination
Anti-Mullerian hormone
Body mass index
Gestation
