摘要
目的探讨多模态磁共振成像(magneticresonanceimaging,MRI)对不同病理分级及分型脑膜瘤的诊断价值。方法回顾性分析2021年1月至2022年5月牡丹江医学院附属红旗医院确诊的58例脑膜瘤患者的影像资料,以病理结果为金标准,观察不同扫描序列对脑膜瘤分级、分型的诊断效能及与病理诊断的一致性。结果病理结果显示,58例脑膜瘤患者世界卫生组织(WorldHealthOrganization,WHO)分级Ⅰ级50例、Ⅱ级5例、Ⅲ级3例。T1加权成像(T1 weighted imaging,T1WI)呈稍低及等信号、T2加权成像(T2weightedimaging,T2WI)呈等及稍高信号时多见于良性脑膜瘤,恶性脑膜瘤T1WI、T2WI一般呈等信号,信号评分对血管瘤型、微囊型及纤维型有鉴别意义。不同WHO分级脑膜瘤的水肿指数、局部脑血流量、表观弥散系数比较差异均有统计学意义(P<0.05);Ⅰ级脑膜瘤与Ⅱ、Ⅲ级脑膜瘤的N-乙酰天冬氨酸(N-acetyl-aspartate,NAA)、胆碱复合物(cholinecompound,Cho)、肌酐(creatinine,Cr)、NAA/Cr、Cho/Cr比较,差异均有统计学意义(P<0.05)。磁敏感加权成像对病灶内出血、微血管及钙化的检出与病理结果有较高的一致性。结论多模态MRI对不同病理分级脑膜瘤的鉴别及分型有较高的临床价值。
Objective To explore the diagnostic value of multimodal magnetic resonance imaging(MRI)in different pathological grades and types of meningiomas.Methods The imaging data of 58 patients with meningioma diagnosed in Hongqi Hospital Affiliated to Mudanjiang Medical University from January 2021 to May 2022 were analyzed retrospectively.Pathological results were used as the gold standard to observe the diagnostic efficacy of different scanning sequences for grades and types of meningioma,and the consistency with pathological diagnosis.Results The pathological results showed that 58 patients with meningioma were classified by the World Health Organization(WHO)as GradeⅠ50 cases,gradeⅡ5 cases,and gradeⅢ3 cases.Benign meningiomas were more common when T1 weighted imaging(T1WI)presented slightly lower and equal signals,and when T2 weighted imaging(T2WI)presented equal and slightly higher signals.Malignant meningioma showed equal signals on T1WI and T2WI.The signal score was significant in differentiating hemangioma type,microcapsule type and fiber type.There were significant differences in edema index,regional cerebral blood flow and apparent diffusion coeffecient of meningiomas of different WHO grades(P<0.05).There were statistically significant differences in N-acetyl-aspartate(NAA),choline compound(Cho),creatinine(Cr),NAA/Cr and Cho/Cr between gradeⅠmeningiomas and gradeⅡandⅢmeningiomas(P<0.05).The detection of intracranial hemorrhage,microvascular and calcification by susceptibility weighted imaging was consistent with the pathological results.Conclusion Multimodal MRI has high clinical value in differentiating and typing meningiomas of different pathological grades.
作者
刘鹤
王晓申
王煜宁
张晓鹏
胡涛
李洪义
王婷
邢健
于泽霏
董智慧
LIU He;WANG Xiaoshen;WANG Yuning;ZHANG Xiaopeng;HU Tao;LI Hongyi;WANG Ting;XING Jian;YU Zefei;DONG Zhihui(Department of Magnetic Resonance,Hongqi Hospital Affiliated to Mudanjiang Medical University,Mudanjiang 157011,Heilongjiang,China;Graduate College of Mudanjiang Medical University,Mudanjiang 157011,Heilongjiang,China;Department of Imaging,the Second Hospital of Mudanjiang Medical University,Mudanjiang 157011,Heilongjiang,China)
出处
《中国现代医生》
2023年第19期19-23,共5页
China Modern Doctor
基金
黑龙江省卫生健康委科研项目(20210909010305)。
关键词
多模态磁共振成像
脑膜瘤
病理分级
临床价值
Multimodal magnetic resonance imaging
Meningioma
Pathological grading
Clinical value
