摘要
目的构建听力正常婴幼儿不同频率短纯音听性脑干反应(TB-ABR)波V强度-潜伏期函数曲线,为临床TB-ABR反应阈的判断提供参考。方法选取40例(80耳)听力正常婴幼儿作为研究对象,月龄3~12月,平均7.2±2.8月。分别选取70、60、50、40、30 dB nHL 5个不同刺激强度进行TB-500、TB-1000、TB-2000和TB-4000 Hz 4个频率的TB-ABR检测,记录不同强度下各频率的波V潜伏期,使用SPSS 26.0进行统计学分析,建立各频率不同强度下的强度-潜伏期函数模型。结果①同一强度不同频率下的波V潜伏期差异均有统计学意义(P<0.05);②阈值强度下不同频率下的波V潜伏期差异均有统计学意义(P<0.05);③同一频率不同强度波V潜伏期差异均有统计学意义(P<0.05);④不同刺激频率下的强度-潜伏期函数模型分别为TB-500 Hz:y=-0.09 x+16.59;TB-1000 Hz:y=-0.07 x+13.73;TB-2000 Hz:y=-0.05 x+10.61;TB-4000 Hz:y=-0.04 x+9.44。结论TB-ABR的波V潜伏期随刺激声频率和/或强度的升高而逐渐缩短,本研究建立的不同频率不同强度下的TB-ABR强度-潜伏期函数模型可为本实验室临床提供参考。
Objective To construct the tone burst auditory brainstem responses(TB-ABR)wave V intensity-latency function curve of different frequencies in infants with normal hearing,and to provide a reference for the determination of clinical TB-ABR response threshold.Methods Forty infants(80 ears)with normal hearing were selected for this study.The age distribution was from 3 to 12 months and the mean age was 7.2±2.8 months.Five different stimulus intensities of 70,60,50,40,and 30 dB nHL were selected for TB-ABR testing at four frequencies of TB-500 Hz,TB-1000 Hz,TB-2000 Hz,and TB-4000 Hz.Wave V latency of each frequency at different intensities were recorded and statistically analyzed using SPSS 26.0 to establish the intensity-latency functional model for each frequency.Results The differences in wave V latencies at different frequencies were statistically significant(P<0.05).The difference in wave V latencies of at different intensities were statistically significant(P<0.05).The differences in wave V latencies at different threshold intensity level were statistically significant(P<0.05).The intensity-latency functional models at different frequencies were TB-500 Hz:y=-0.09 x+16.59;TB-1000 Hz:y=-0.07 x+13.73;TB-2000 Hz:y=-0.05 x+10.61;TB-4000 Hz:y=-0.04 x+9.44,respectively.Conclusion The wave V latency of TB-ABR gradually shortens with the increase of the frequency and intensity.The intensity-latency functional model of TB-ABR at different frequencies and intensities established in this study can provide a reference for clinical practice.
作者
马孝宝
沈佳丽
汪玮
王璐
孙进
贺宽
陈向平
杨军
陈建勇
Ma Xiaobao;Shen Jiali;Wang Wei;Wang Lu;Sun Jin;He Kuan;Chen Xiangping;Yang Jun;Chen Jianyong(Department of Otolaryngology-Head&Neck Surgery,Xinhua Hospital Affiliated to Shanghai Jiaotong University School of Medicine,Ear Institute Shanghai Jiaotong University School of Medicine Shanghai Key Laboratory of Translational Medicine of Ear and Nose Disease,Shanghai,200092,China)
出处
《听力学及言语疾病杂志》
CAS
CSCD
北大核心
2023年第4期299-304,共6页
Journal of Audiology and Speech Pathology
基金
上海市科委项目(21S31900600)
新华医院院级临床研究培育基金(21XHDB02)。
