摘要
目的 分析一次性根管治疗与多次法根管治疗对牙体牙髓病的效果。方法 60例牙体牙髓病患者,随机分为研究组和对照组,每组30例。对照组应用多次法根管治疗方式进行治疗,研究组应用一次性根管治疗方式进行治疗。比较两组患者临床疗效、不良反应(根尖脓肿、牙龈发炎、咬合不适、牙齿疼痛)发生率,治疗前后咀嚼功能(咬合力、咀嚼效率)、疼痛(咬合性疼痛、自发性疼痛)评分、炎性因子[白细胞介素-2(IL-2)、白细胞介素-6(IL-6)、肿瘤坏死因子-α(TNF-α)]水平。结果 研究组治疗总有效率96.67%高于对照组的76.67%,差异具有统计学意义(P<0.05)。治疗后,研究组咬合力(145.32±3.50)Ibs、咀嚼效率(92.45±1.63)%均高于对照组的(117.24±6.55)Ibs、(84.65±2.13)%,差异均具有统计学意义(P<0.05)。研究组不良反应发生率3.33%低于对照组的26.67%,差异具有统计学意义(P<0.05)。治疗后,研究组患者咬合性疼痛、自发性疼痛评分分别为(2.04±0.50)、(1.80±0.30)分,均低于对照组的(2.82±0.61)、(2.45±0.53)分,差异均具有统计学意义(P<0.05)。治疗后,两组患者IL-2、IL-6、TNF-α水平均低于治疗前,且研究组患者IL-2(5.03±0.62)μg/L、IL-6(13.98±1.44)ng/L、TNF-α(20.04±2.16)ng/L均低于对照组的(6.25±0.74)μg/L、(18.76±2.18)ng/L、(29.88±3.17)ng/L,差异均具有统计学意义(P<0.05)。结论 牙体牙髓病患者应用一次性根管治疗效果更好,可有效降低不良反应发生率与炎性因子水平,改善咀嚼功能,减轻痛苦程度,具有应用价值。
Objective To analyze the effect of disposable root canal therapy and multiple-visit root canal therapy in the treatment of dental pulp disease.Methods A total of 60 patients with dental pulp disease were randomly divided into research group and control group,with 30 cases in each group.The control group was treated with multiple-visit root canal therapy,and the research group was treated with disposable root canal therapy.Both groups were compared in terms of clinical efficacy,incidence of adverse reactions(apical abscess,gingival inflammation,occlusal discomfort,dental pain),masticatory function(bite force,masticatory efficiency),pain(occlusal pain,spontaneous pain)scores,inflammatory factors[interleukin-2(IL-2),interleukin-6(IL-6),tumor necrosis factor-α(TNF-α)]level before and after treatment.Results The total effective rate of the research group was 96.67%,which was higher than that of 76.67%of the control group,and the difference was statistically significant(P<0.05).After treatment,the bite force of(145.32±3.50)Ibs and masticatory efficiency of(92.45±1.63)%in the research group were higher than those of(117.24±6.55)Ibs and(84.65±2.13)%in the control group,and the differences were statistically significant(P<0.05).The incidence of adverse reactions of 3.33%in the research group was lower than that of 26.67%in the control group,and the difference was statistically significant(P<0.05).After treatment,the scores of occlusal pain and spontaneous pain in the research group were(2.04±0.50)and(1.80±0.30)points,which were lower than those of(2.82±0.61)and(2.45±0.53)points in the control group,and the differences were statistically significant(P<0.05).After treatment,the levels of IL-2,IL-6 and TNF-αin the two groups were lower than those before treatment in this group;the research group had IL-2 of(5.03±0.62)μg/L,IL-6 of(13.98±1.44)ng/L and TNF-αof(20.04±2.16)ng/L,which were lower than those of(6.25±0.74)μg/L,(18.76±2.18)ng/L and(29.88±3.17)ng/L in the control group;all the differences were stati
作者
朴维英
翟荣萍
PIAO Wei-ying;ZHAI Rong-ping(Stomatology Department,Inner Mongolia Autonomous Region People's Hospital,Hohhot 010010,China)
出处
《中国现代药物应用》
2023年第11期55-58,共4页
Chinese Journal of Modern Drug Application
关键词
一次性根管治疗
多次法根管治疗
牙体牙髓病
咀嚼功能
炎性因子水平
Disposable root canal therapy
Multiple-visit root canal therapy
Dental pulp disease
Masticatory function
Inflammatory factor levels
