摘要
目的:研究超声极速成像技术在代谢综合征(MS)患者的颈动脉狭窄评估中的应用价值。方法:选取医院收治的106例MS患者,将合并颈动脉狭窄的患者纳入观察组(65例),将无合并颈动脉狭窄得患者纳入对照组(41例)。使用超声极速成像技术检测两组颈总动脉收缩期开始时的脉搏波传导速度(PWVBS)、收缩期结束时的脉搏波传导速度(PWVES)以及颈动脉内膜中层厚度(IMT)。比较两组颈动脉PWVBS、PWVES及IMT,以及不同颈动脉狭窄程度MS患者双侧颈动脉PWVBS、PWVES及IMT;以受试者工作特征(ROC)曲线分析PWVBS、PWVES及IMT预测MS发生颈动脉狭窄的价值,并分析PWVBS、PWVES及IMT联合诊断MS患者发生颈动脉狭窄的效能;以Spearman系数分析PWVBS、PWVES及IMT与颈动脉狭窄程度的相关性。结果:观察组PWVBS、PWVES及IMT值均较大,与对照组相比差异有统计学意义(t=2.163,t=3.849,t=3.467;P<0.05);观察组65例患者中轻度狭窄17例,中度狭窄28例,重度狭窄20例,不同狭窄程度PWVBS相比,轻度狭窄<中度狭窄<重度狭窄,不同狭窄程度PWVES相比,轻度狭窄<中度狭窄<重度狭窄;左侧颈动脉轻度、中度及重度狭窄的PWVBS均较大,与右侧颈动脉PWVBS相比差异有统计学意义(t=2.068,t=3.167,t=3.067;P<0.05);左侧颈动脉轻度、中度、重度狭窄的PWVES均较大,与右侧颈动脉PWVES相比差异有统计学意义(t=2.107,t=2.857,t=3.240;P<0.05);经ROC分析,最佳截断值PWVBS≥5.395 m/s,PWVBS≥7.375 m/s,IMT≥0.489 mm;经一致性分析,PWVBS、PWVES及IMT联合预测MS患者发生颈动脉狭窄的灵敏度为0.892、特异度为0.878、准确率为0.887、Kappa=0.763;经相关性分析,PWVBS、PWVES及IMT与颈动脉狭窄程度呈正相关(r=0.526,r=0.575,r=0.502;P<0.05)。结论:PWVBS、PWVES及IMT在合并颈动脉狭窄的MS患者中数值较大,是预测MS患者发生颈动脉狭窄的最佳截断值,且PWVBS、PWVES及IMT与颈动脉狭窄程度呈正相关,超声极速成像技术可用于�
Objective:To study the value of ultrasound velocity imaging technique in assessing carotid artery stenosis of patients with metabolic syndrome(MS).Methods:A total of 106 MS patients admitted to the hospital were selected and they divided into observation group(65 patients with carotid stenosis)and control group(41 patients without carotid stenosis)according to whether patients companied with carotid artery stenosis.The ultrasound velocity imaging technique was adopted to detect pulse wave velocity at the beginning of systole(PWVBS),pulse wave velocity at the end of systole(PWVES)and intima-media-thickness(IMT)of carotid arteries of two groups.The PWVBS,PWVES and IMT of carotid artery between two groups were compared,and the above indicators among patients with different degrees of bilateral carotid stenosis were further compared.The receiver operating characteristics(ROC)was adopted to respectively analyze the values of PWVBS,PWVES and IMT in predicting the occurrence of carotid stenosis in MS patients,and the efficiency of the combined diagnosis of PWVBS,PWVES and IMT for the occurrence of carotid stenosis in MS patients.The Spearman coefficient was used to respectively analyze the correlations between PWVBS,PWVES and IMT and the degree of carotid stenosis.Results:The values of PWVBS,PWVES and IMT of the observation group were significantly larger than those of control group(t=2.163,t=3.849,t=3.467,P<0.05),respectively.Among the 65 patients in the observation group,there were 17 cases of mild stenosis,28 cases of moderate stenosis and 20 cases of severe stenosis.In the comparison of PWVBS among different stenosis degrees,the mild stenosis<the moderate stenosis<the severe stenosis.In the comparisons of PWVES among different stenosis degrees,the mild stenosis<the moderate stenosis<the severe stenosis.The PWVBS values of mild,moderate and severe stenosis of left side of carotid artery were significantly larger than those of right side of carotid artery(t=2.068,t=3.167,t=3.067,P<0.05),respectively.The PWVES values o
作者
高雷
焦杨
刘玮
薛阳利
王月
魏玲云
张美丽
张静
杨妙妍
GAO Lei;JIAO Yang;LIU Wei(Department of Endocrinology,The Second Affiliated Hospital of Xi'an Jiaotong University,Xi'an 710004,China;不详)
出处
《中国医学装备》
2023年第4期65-69,共5页
China Medical Equipment
基金
陕西省重点研发计划(2020SF-165)“西安地区50岁以上人群(特别是50岁以上女性)代谢综合征患病情况研究”。
