摘要
脑水肿属中医“中风”“真头痛”等范畴,中医多从瘀、虚、热等角度理解其核心病机,多治以温阳利水、化瘀行水等。五苓散被誉为“伤寒利水第一方”,可利水渗湿、温阳化气,临床可用于治疗颅脑外伤、脑出血、脑梗死及颅内占位等各种原因引起的脑水肿,并取得显著疗效,主要通过改善脑组织细胞能量供应、清除氧自由基及钙离子、缓解炎症因子对脑组织的损害、调控水通道蛋白等发挥治疗作用。
Brain edema belongs to the category of"stroke"and"true headache",while Traditional Chinese Medicine mostly understands its core disease mechanisms from the perspectives of stasis,deficiency,and heat,and mostly treats the disease by using warming yang to induce diuresis and eliminating stasis to remove water.Wuling Powder has been lauded as the"first party to typhoid and relieving diuresis",which is used to cure clearing damp and promoting diuresis and warming yang and transforming qi,and has been clinically used in the treatment of brain edema caused by various causes such as head trauma,intracerebral hemorrhage,cerebral infarction,and intracranial space occupying,all with remarkable efficacy.Wuling Powder improves cellular energy supply,scavenges excess oxygen radicals and calcium ions in brain tissue,and reduces the damage to brain tissue caused by vascular inflammatory factors and regulates aquaporins and vascular endothelial growth factor,thereby achieving therapeutic effects.
作者
薄晗
赵晓平
范小璇
于娟
张梦洁
孙雯
Bo Han;Zhao Xiaoping;Fan Xiaoxuan;Yu Juan;Zhang Mengjie;Sun Wen(Master Degree Student of Grade 2020,Shaanxi University of Chinese Medicine,Xianyang 712000,China;Department of Neurosurgery,Affiliated Hospital of Shaanxi University of Chinese Medicine,Xianyang 712000,China;Master Degree Student of Grade 2019,Shaanxi University of Chinese Medicine,Xianyang 712000,China)
出处
《国际中医中药杂志》
2023年第2期243-247,共5页
International Journal of Traditional Chinese Medicine
基金
国家重点研发计划项目(2017YFC1703500、2017YFC1703502)
国家自然科学基金项目(81873288)
陕西省中医药管理局2020年中西医结合临床协作创新项目(2020-ZXY-007)
陕西省重点研发计划项目(2019ZDLSF04-06-01)
陕西省中医脑病临床医学研究中心建设项目(201704)
陕西中医药大学学科创新团队建设项目(2019-YL15)。
关键词
五苓散
脑水肿
作用机制
临床应用
综述
Wu Ling San
Brain edema
Action mechanism
Clinical application
Review
