摘要
目的基于荟萃分析评价术中联合植入囊袋张力环(CTR)对高度近视患者白内障手术疗效的影响。方法全面检索PubMed、Embase、Web of Science、The Cochrane Library、中国知网、万方、维普等7个数据库,检索时间范围为1990年1月1日至2022年3月20日,收集CTR在高度近视患者白内障手术中应用的随机对照试验和非随机对照试验。2名研究人员根据纳入和排除标准,独立检索文献、提取数据及进行方法学质量评价,采用Review Manager 5.4进行荟萃分析。结果最终纳入8篇文献,共涉及1292例(1630眼)患者。荟萃分析结果显示,在改善患者最佳矫正视力(BCVA)方面,术后1个月、3个月、6个月CTR联合人工晶状体(IOL)植入组患者的BCVA均显著优于IOL植入组(均为P<0.05);在IOL倾斜角、偏心量方面,术后6个月时CTR联合IOL植入组患者较IOL植入组均显著降低(均为P<0.05);晶状体前囊口面积方面,术后3个月时CTR联合IOL植入组患者大于IOL植入组(P=0.048);术后PCO发生率方面,CTR联合IOL植入组患者显著低于IOL植入组(P<0.00001);术后3个月时CTR联合IOL植入组患者角膜内皮细胞密度与IOL植入组相比差异无统计学意义(P=0.48)。结论对于高度近视患者,在白内障术中植入CTR有助于患者获得更好的BCVA、减少术后IOL倾斜与偏心、降低PCO以及囊袋皱缩的发生。
Objective To evaluate the effect of implanted capsular tension ring(CTR)on the cataract surgery of patients with high myopia.Methods Seven databases,including PubMed,Embase,Web of Science,the Cochrane Library,CNKI,Wanfang Data and Weipu,were comprehensively searched with a time range from January 1,1990 to March 20,2022.Randomized controlled trials and non-randomized controlled trials of the application of CTR in cataract surgery of patients with high myopia were collected.Two researchers independently searched the literatures,extracted the data,and assessed methodological quality according to the inclusion and exclusion criteria.Meta-analysis was performed using Review Manager 5.4.Results Eight articles were finally included,involving 1292 patients(1630 eyes).Meta-analysis showed that the best corrected visual acuity(BCVA)of patients who underwent CTR combined with intraocular lens(IOL)implantation was significantly higher than that in the patients who underwent IOL implantation at 1 month,3 months and 6 months after the surgery(all P<0.05).In the patients who underwent CTR combined with IOL implantation,the angle of inclination and eccentricity of IOL were significantly lower than those in the patients who underwent IOL implantation at 6 months after the surgery(both P<0.05).The anterior lens capsular orifice area in the patients who underwent CTR combined with IOL implantation was significantly higher than that in the patients who underwent IOL implantation 3 months after the surgery(P=0.048);the incidences of posterior capsule opacification(PCO)in the patients who underwent CTR combined with IOL implantation was significantly lower than that in the patients underwent IOL implantation(P<0.00001).There was no significant difference in the endothelial cell density between the two groups 3 months after the surgery(P=0.48).Conclusion For high myopic patients,implanting CTR in cataract surgery is conducive to a higher BCVA,less inclination and eccentricity,lower incidences of PCO and capsular bag shrinkage.
作者
郝壮
赵超
蒋孟琪
张泸宁
马济远
何梦梅
周健
HAO Zhuang;ZHAO Chao;JIANG Mengqi;ZHANG Luning;MA Jiyuan;HE Mengmei;ZHOU Jian(Department of Ophthalmology,Xijing Hospital,Air Force Medical University,Eye Institute of PLA,Xi’an 710032,Shaanxi Province,China;Department of Clinics,Aviation University of Air Force,Changchun 130000,Jilin Province,China)
出处
《眼科新进展》
CAS
北大核心
2023年第1期47-52,共6页
Recent Advances in Ophthalmology
基金
空军军医大学临床研究项目(编号:2021LC2219)
空军军医大学第一附属医院学科助推计划(编号:XJZT19D07)。
关键词
高度近视
囊袋张力环
白内障手术
荟萃分析
人工晶状体倾斜
人工晶状体偏心
后发性白内障
囊袋皱缩
high myopia
capsular tension ring
cataract surgery
meta-analysis
inclination of intraocular lens
eccentricity of intraocular lens
posterior capsule opacification
capsular bag shrinkage
