摘要
目的了解洛阳市某区人群乙型肝炎病毒(HBV)血清标志物的流行状况。方法采用横断面调查方法,通过随机抽样方法抽取洛阳市某区一个镇,在该镇随机选取0~79岁人群628名作为调查对象,采集血清标本,检测乙肝表面抗原(HBsAg)、乙肝表面抗体(HBsAb)、乙肝e抗原(HBeAg)、乙肝e抗体(HBeAb)和乙肝核心抗体(HBcAb)。结果628名调查对象中,HBsAg、HBsAb、HBeAg、HBeAb、HBcAb阳性率分别为0.16%、65.92%、0.32%、1.75%、28.98%,0~4岁、5~14岁、15~39岁和40~79岁人群HBsAb阳性率分别为94.92%、73.87%、51.25%和39.38%(χ^(2)=140.116,P<0.05),HBc Ab阳性率分别为28.93%、18.92%、24.38%和40.63%(χ^(2)=5.016,P<0.05);男女HBsAb阳性率分别为70.16%和61.92%(χ^(2)=4.746,P<0.05);各职业人群HBsAb、HBcAb阳性率差异有统计学意义(确切概率法P<0.05);不同教育程度人群HBsAb阳性率差异有统计学意义(确切概率法P<0.05)。结论洛阳市某区乙肝防控成绩显著,有必要对成人采取综合措施,降低乙肝的传播风险。
Objective To understand the prevalence of serum hepatitis B virus(HBV)biomarkers in a district in Luoyang.Methods We used a cross-sectional design to randomly select people with 0-79 years of age in a district in Luoyang.A questionnaire survey was conducted,and 628 subjects were investigated.We tested serum samples for HBV surface antigen(HBsAg),HBV surface antibody(HBsAb),HBV e antigen(HBeAg),HBV e antibody(HBeAb),and HBV core antibody(HBcAb).Results A total of 628 people were investigated,and the positive rates of HBsAg,HBsAb,HBeAg,HBeAb and HBcAb were0.16%,65.92%,0.32%,1.75%and 28.98%,respectively.The positive rates of HBsAb for the groups of 0-4,5-14,15-39 and40-79-year-olds were 94.92%,73.87%,51.25%and 39.38%,respectively,with significant difference(χ^(2)=140.116,P<0.05);the positive rates of HBc Ab for the groups of 0-4,5-14,15-39 and 40-79-year-olds were 28.93%、18.92%、24.38%and40.63%,respectively,with significant difference(χ^(2)=5.016,P<0.05).There were statistically significant differences in the positive rates of HBsAb between gender(χ^(2)=4.746,P<0.05),among occupations(P<0.05)and education level(P<0.05).Conclusions Hepatitis B prevention and control in the studied district in Luoyang has made certain achievements,but it is still necessary to implement comprehensive intervention measures to reduce the risk of hepatitis B infection among adults.
作者
王伟
田鹏
WANG Wei;TIAN Peng(Luoyang Center for Disease Control and Prevention,Luoyang,Henan 471023,China)
出处
《河南预防医学杂志》
2022年第12期935-938,共4页
Henan Journal of Preventive Medicine
关键词
乙型肝炎
血清
标志物
乙肝疫苗
预防接种
Hepatitis B
Serum
biomarker
Hepatitis B vaccine
Vaccination
