摘要
目的分析2017-2020年驻马店市疑似预防接种异常反应(adverse event following immunization,AEFI)的发生特征。方法通过中国免疫规划信息管理系统收集2017-2020年驻马店市所有AEFI个案及疫苗接种剂次数,计算报告发生率,采用描述流行病学分析AEFI发生特征。结果2017-2020年驻马店市共报告9815例,报告发生率73.57/10万剂次。其中一般反应9624例,占98.05%;异常反应161例,占1.64%;男女性别比为1.16∶1,0~1岁儿童占71.34%,不同年龄组差异有统计学意义(P<0.001);每月均有报告;9个县区均有病例报告,确山县报告发生率最高,地区差异有统计学意义(P<0.001);异常反应以过敏性皮疹为主,占78.26%,报告发生率为0.94/10万剂;接种后1天内发生AEFI占70.68%;99.95%的转归是痊愈。结论2017-2020年驻马店市AEFI以一般反应为主,疫苗安全性较好,需加强宣传培训,进一步提高监测和处置能力。
Objective To analyze the occurrence characteristics of adverse event following immunization(AEFI)in Zhumadian city from 2017-2020.Methods All AEFI cases and vaccination doses in Zhumadian city from 2017 to 2020 were collected through the China Immunization Program Information Management System.The occurrence characteristics of AEFIs were analyzed using descriptive epidemiological method.Results A total of 9815 AEFI cases were reported in Zhumadian city in2017-2020,with a reported incidence of 73.57/105doses.There were 9624 cases of general reaction,accounting for 98.05%,161 cases(1.64%)had abnormal reactions.The sex ratio of male to female was 1.16∶1,and most of them were children aged 0-1year,accounting for 71.34%.It had a statistical significance among the age groups(P<0.001).Every month had cases reported.Cases were reported from all nine counties,and the highest incidence was reported in Queshan,and the differences among the regions were statistically significant(P<0.001).Allergic rash was the main abnormal reaction,accounting for 78.26%,with a reported incidence of 0.94/105doses.AEFI cases occurring within 1 day after inoculation accounted for 70.68%of the total cases.The recovery rate was 99.95%.Conclusion In 2017-2020,the AEFI in Zhumadian city was mainly general reaction,and the vaccine safety was good.Therefore,publicity and training should be strengthened to further improve the monitoring and disposal capacity.
作者
李敬
时凯
韩艳伟
孙婷婷
LI Jing;SHI Kai;HAN Yanwei;SUN Tingting(Zhumadian Center for Disease Control and Prevention,Zhumadian,Henan 463000,China)
出处
《河南预防医学杂志》
2022年第11期851-855,共5页
Henan Journal of Preventive Medicine
关键词
疑似预防接种异常反应
监测
报告发生率
Adverse events following immunization
Surveillance
Reported incidence
