摘要
目的了解聊城市疑似预防接种异常反应(AEFI)发生特征,评价AEFI监测系统运转情况和疫苗的安全性。方法通过中国AEFI监测管理系统,收集聊城市2018~2020年AEFI个案数据,采用描述性方法对系统进行评价,对AEFI病例进行流行病学分析。结果2018~2020年聊城市累计报告AEFI个案4688例,县(市、区)覆盖率、48h报告率、48h调查率均为100.00%;一般反应占99.38%,异常反应占0.45%(21例)。男女性别比为1.34∶1;≤1岁儿童占72.82%。国家免疫规划(NIP)疫苗占82.55%;94.16%发生在接种后≤1d;报告例数居前三位的疫苗分别是无细胞百白破疫苗(1515例)、乙脑减毒活疫苗(589例)和麻腮风疫苗(326例)。全市疫苗AEFI总体报告发生率为70.14/10万剂。结论2018~2020年聊城市AEFI监测系统运转良好,敏感性和监测质量稳步推进。
Objective To understand the features of adverse vents following immunization(AEFI)in Liaocheng city,and evaluate the implementation of AEFI system.Methods The data of AEFI cases in Liaocheng city during 2018-2020 were collected through China AEFI Monitoring and Management System,and the system was evaluated using descriptive method,and the epidemiological analysis of AEFI cases was conducted.Results A total of 4688 cases were reported each year in the 8 districts of the city during 2018-2020.Reporting rate and investigation rate within 48 hours were both100.00%.99.38%of cases were minor vaccine reaction,while 0.45%(21 cases)were rare and serious vaccine reaction.The sex ratio of males to females was 1.34:1,and 72.82%of cases were children under 1 year old.National Immunization Program(NIP)vaccine took up 82.55%.94.16%of cases occurred≤1 day after vaccination.The top 3 reported vaccines were DPT(1515 cases),JEV(589 cases)and MMR(326 cases).The overall reporting rate of AEFI in the whole city was 70.14/105 doses.Conclusion From 2018 to 2020,the AEFI monitoring system in Liaocheng city operated well,and the sensitivity and monitoring quality were steadily advanced.
作者
刘淑霞
张金忠
刘中华
刘婷婷
姜祥坤
贾金丽
侯怡哲
梁伟
LIU Shu-xia;ZHANG Jin-zhong;LIU Zhong-hua;LIU Ting-ting;JIANG Xiang-kun;JIA Jin-li;HOU Yi-zhe;LIANG Wei(Liaocheng City Center for Disease Control and Prevention,Liaocheng,Shandong,252000,China;不详)
出处
《预防医学论坛》
2021年第10期737-739,743,共4页
Preventive Medicine Tribune
基金
山东省医药卫生科技发展计划项目(项目编号:2017WS642)
山东预防医学会智飞疾病预防控制技术研究基金项目(项目编号:LYH2017-15、LYH2017-30、LYH2017-14)
。
关键词
疑似预防接种异常反应
监测
Adverse events following immunization
Surveillance
