摘要
以聚乳酸(PLLA)和醋酸纤维素(CA)为成膜材质,在一定温度和湿度条件下,利用水蒸气辅助法成功制备PLLA/CA蜂窝状复合多孔膜。研究溶剂种类、湿度、聚合物浓度、聚合物比例和成膜温度等条件对蜂窝孔形成的影响。实验结果表明环境湿度从43%增加至91%,蜂窝孔的孔径从1.67±1.34μm增加至5.01±1.34μm,且孔径大小与湿度呈现一阶线性关系。通过理论推导得到拟合直线的斜率为0.068,即环境湿度每增加1%,孔直径增加0.068μm,孔直径的增长率为0.068μm/%。聚合物浓度从1 wt%增加至6 wt%,蜂窝孔的孔径呈现先增大后减小的趋势。温度在10~50℃范围内,环境温度对孔形貌及其孔径并无太大影响。纯PLLA蜂窝状多孔膜的水接触角为(128.1±2.4)°,随着体系中CA含量增加,多孔膜的水接触角降低。当PLLA/CA=5∶5时,水接触角为(50.2±1.4)°,说明体系中加入一定量CA后,多孔膜的亲水性提高,亲水性的提高有利于细胞在其表面的粘附、迁移、繁殖和生长。
PLLA/CA honeycomb composite porous membranes were prepared via Breath Figure method under certain humidity and temperature conditions with PLLA and CA as film materials. The effects of factors, such as solvent, relative humidity, polymer concentration, the ratio of polymer, and temperature, on the pore patterns and sizes were investigated. The results show that the pore size of PLLA/CA membranes increases from 1.67±1.34 μm to 5.01±1.34 μm with increasing relative humidity from 43% to 91%. The relationship of pore size and the relative humidity is presented first order liner relationship. Moreover, the slope of straight line is 0.068, which indicates that for every 1% in relative humidity, the pore size increases by 0.068 in this system. When the polymer concentration increases from 1 wt% to 6 wt%, the pore size of honeycomb increases first and then decreases. When the temperature is in the range of 10~50 ℃, the ambient temperature has no significant effect on the pore morphology and size. The water contact angle of pure PLLA honeycomb membrane is 128.1°±2.4°. With the increase of CA content, the water contact angle of porous membrane decreases. When PLLA/CA=5∶5, the water contact angle was 50.2°±1.4°, indicating that a certain amount of CA was added into the system, the hydrophilicity of the porous membrane was improved, which was conducive to the adhesion, migration, reproduction and growth of cells on its surface.
作者
赵瑨云
穆寄林
丁晓红
徐婕
胡家朋
林皓
付兴平
ZHAO Jin-yun;MU Ji-lin;DING Xiao-hong;XU Jie;HU Jia-peng;LIN Hao;FU Xing-ping(Fujian Provincial Key laboratory of Eco-Industrial Green Technology,College of Ecological and Resources Engineering,Wuyi University,Wuyishan 354300,China)
出处
《高分子通报》
CAS
CSCD
北大核心
2022年第10期131-137,共7页
Polymer Bulletin
基金
国家自然科学基金(51406141)
福建省自然科学基金(2020J01412、2020J01414)
南平市基金(2019J06)
南平市产业研究院(N2020Z012)。
