摘要
目的分析妊娠期糖尿病患者不同孕周终止妊娠对新生儿低血糖发生率和妊娠结局的影响。方法回顾性分析不同孕周终止妊娠的240例妊娠期糖尿病患者的临床资料,其中以37~38周终止妊娠患者为A组、39~40周终止妊娠患者为B组、>40周终止妊娠患者为C组,每组80例。分析三组新生儿低血糖发生情况以及母婴结局情况。结果A组、B组、C组新生儿低血糖发生率分别为8.75%、1.25%、10.00%,其中B组新生儿低血糖发生率低于A组、C组,差异均有统计学意义(P<0.05),A组与C组比较差异无统计学意义(P>0.05)。A组、B组、C组孕妇剖宫产率分别为17.50%、20.00%、35.00%,其中A组、B组均低于C组,差异均有统计学意义(P<0.05);A组与B组比较差异无统计学意义(P>0.05)。A组、B组、C组孕妇产后不良结局发生率分别为10.00%、20.00%、48.75%,其中A组、B组均低于C组,差异均有统计学意义(P<0.05);A组与B组比较差异无统计学意义(P>0.05)。三组新生儿不良结局发生率比较差异均无统计学意义(P>0.05)。结论在对妊娠期糖尿病患者在有效控制血糖的基础上,选择39~-40周终止妊娠,可降低新生儿低血糖发生率和产妇产后不良结局,保证母婴安全。
Objective To analyze the effect of pregnancy termination at different gestational weeks on the incidence of neonatal hypoglycemia and pregnancy outcomes in patients with gestational diabetes mellitus.Methods The clinical data of 240 patients with gestational diabetes mellitus who terminated pregnancy at different gestational weeks were retrospectively analyzed.The patients who terminated pregnancy at 37-38 weeks were group A,those who terminated pregnancy at 39-40 weeks were group B,and those who terminated pregnancy at>40 weeks were group C,80 cases in each group.The incidence of neonatal hypoglycemia and maternal and infant outcomes in the three groups were analyzed.Results The incidence of neonatal hypoglycemia in group A,B and C were 8.75%,1.25%and 10.00%respectively,and the incidence of neonatal hypoglycemia in group B was lower than that in group A and C,the differences were statistically significant(P<0.05),there was no signifcant difference between group A and group C(P>0.05).The cesarean section rates of pregnant women in group A,group B,and group C were 17.50%,20.00%,and 35.00%,respectively.Group A and group B were lower than group C,and the differences were statistically significant(P<0.05),there was no significant difference between group A and group B(P>0.05).The incidences of adverse postpartum outcomes of pregnant women in group A,group B,and group C were 10.00%,20.00%,and 48.75%,respectively,among which group A and group B were lower than those in group C,and the differences were statistically significant(P<<0.05);there was no significant diference between group A and group B(P>0.05).There was no significant difference in the incidence of neonatal adverse outcomes among the three groups(P>0.05).Conclusion On the basis of effective control of blood sugar in patients with gestational diabetes mellitus,choosing to terminate pregnancy at 39-40 weeks can reduce the incidence of neonatal hypoglycemia and adverse maternal postpartum outcomes,and ensure the safety of mothers and babies.
作者
朱明进
Zhu Mingjin(Department of Obstetrics,Huai'an Maternal and Child Health Hospital,Huaian 223002,China)
出处
《实用妇科内分泌电子杂志》
2022年第14期4-7,共4页
Electronic Journal of Practical Gynecological Endocrinology
关键词
妊娠期糖尿病
孕周
终止妊娠
新生儿低血糖
妊娠结局
Gestational diabetes
Gestational age
Termination of pregnancy
Neonatal bhypoglycemia
Pregnancy outcome