摘要
目的比较不同浓度罗哌卡因在无痛分娩中的应用效果。方法抽取2020年1月至2022年1月驻马店市中心医院收治的需行无痛分娩的产妇300例,将其按随机数字表法分为A组、B组、C组,每组100例。A组予以0.08%浓度罗哌卡因与舒芬太尼混合液;B组予以0.10%浓度罗哌卡因与舒芬太尼混合液;C组予以0.12%浓度罗哌卡因与舒芬太尼混合液。比较三组产后出血量、总产程、镇痛起效时间、视觉模拟评分法(VAS)评分、产妇生命体征、产妇不良反应及新生儿Apgar评分。结果三组产后出血量、总产程比较差异未见统计学意义(P>0.05);C组镇痛起效时间[(2.21±0.71)min]短于A组[(4.19±1.30)min]、B组[(2.82±0.93)min](P<0.05);镇痛后1 h、90 min,C组VAS评分低于A组、B组(P<0.05);麻醉后,C组舒张压、收缩压、心率均低于A组、B组(P均<0.05);三组不良反应发生率比较差异未见统计学意义(P>0.05);出生后1 min、5 min、10 min,三组新生儿Apgar评分比较差异未见统计学意义(P>0.05)。结论0.12%浓度罗哌卡因应用于产妇无痛分娩中,可缩短镇痛起效时间,提高镇痛效果,并可稳定产妇生命体征,且对新生儿健康状况无较大影响。
Objective To compare the application of ropivacaine with different concentrations in painless delivery.Methods A total of 300 pregnant women who need painless delivery in Zhumadian Central Hospital from January 2020 to January 2022 were divided into group A,group B and group C by random number table method,with 100 cases in each group.Group A was given a mixture of 0.08%ropivacaine and sufentanil,group B was given a mixture of 0.10%ropivacaine and sufentanil,while group C was given a mixture of 0.12%ropivacaine and sufentanil.The amount of postpartum hemorrhage,total stage of labor,onset time of analgesia,visual analogue scale(VAS)score,maternal vital signs,maternal adverse reactions and neonatal Apgar score were compared among the three groups.Results There was no significant difference in the amount of postpartum hemorrhage and total stage of labor among the three groups(P>0.05).The onset time of analgesia in the group C was(2.21±0.71)min shorter than(4.19±1.30)min in the group A and(2.82±0.93)min in the group B(P<0.05).At 1 h and 90 min after analgesia,the VAS scores of the group C was lower than that of the group A and group B(P<0.05).After anesthesia,the diastolic blood pressure,systolic blood pressure and heart rate in the group C were lower than those in the group A and group B(all P<0.05).There was no significant difference in maternal adverse reactions among the three groups(P>0.05).There was no significant difference in Apgar score among the three groups at 1 min,5 min and 10 min after birth(P>0.05).Conclusions The application of 0.12%ropivacaine in painless delivery can shorten the onset time of analgesia,improve the analgesic effect,stabilize vital signs,and have no significant impact on the health status of newborns.
作者
樊彩霞
王震
赵晨璐
Fan Caixia;Wang Zhen;Zhao Chenlu(Department of Anesthesiology,Zhumadian Central Hospital,Zhumadian 463000,China)
出处
《中国实用医刊》
2022年第17期68-71,共4页
Chinese Journal of Practical Medicine
关键词
无痛分娩
罗哌卡因
镇痛起效时间
镇痛效果
Painless childbirth
Ropivacaine
Onset time of analgesia
Analgesic effect
