摘要
目的探讨老年抑郁症患者复发影响因素。方法选取浙江省宁波市康宁医院2019年2月至2020年2月收治的220例老年抑郁症患者作为研究对象,经过随访1年后,根据随访结果将患者分为复发组(90例)和未复发组(130例)。比较两组性别、年龄、婚姻状况、发病形式、家族病史、伴有躯体疾病、认知功能障碍、治疗依从性、重大生活事件、睡眠障碍、发病次数、总病程情况。采用多因素非条件logistic回归分析,观察影响老年抑郁症复发的危险因素情况。结果两组婚姻状况、发病形式、家族病史、伴有躯体疾病、认知功能障碍、治疗依从性、重大生活事件、睡眠障碍、发病次数比较,差异有统计学意义(P<0.05)。通过多因素非条件Logistic回归法进行逐步回归分析,伴有躯体疾病(OR=3.934,95%CI:2.706~5.159)、认知功能障碍(OR=2.336,95%CI:1.561~3.118)、治疗依从性(OR=3.458,95%CI:2.330~4.568)、重大生活事件(OR=5.440,95%CI:3.987~6.896)、睡眠障碍(OR=1.989,95%CI:1.268~2.721)是老年抑郁症患者复发的危险因素(P<0.05)。结论老年抑郁症患者复发在临床常见,伴有躯体疾病、认知功能障碍、治疗依从性、重大生活事件、睡眠障碍是患者复发的危险因素,应针对性干预,降低复发率。
Objective To investigate the influencing factors of relapse in elderly patients with depression.Methods A total of 220 elderly patients with depression who were admitted to Ningbo Kangning Hospital,Zhejiang Province from February 2019 to February 2020 were selected as the research subjects.After a year of follow-up,the patients were divided into recurrence group(90 cases)and non-relapse group(130 cases)according to the follow-up results.The gender,age,marital status,onset form,family history,associated physical diseases,cognitive dysfunction,treatment compliance,major life events,sleep disturbances,the number of onsets,and the total course of the disease were compared between the two groups.Multivariate unconditional logistic regression analysis was used to observe the risk factors affecting the recurrence of depression in the elderly.Results There were statistically significant differences in marital status,onset form,family medical history,associated physical disease,cognitive dysfunction,treatment compliance,major life events,sleep disturbance,and incidence of disease between the two groups(P<0.05).Stepwise regression analysis was performed by multivariate unconditional logistic regression,associated with physical disease(OR=3.934,95%CI:2.706-5.159),cognitive impairment(OR=2.336,95%CI:1.561-3.118),treatment compliance(OR=3.458,95%CI:2.330-4.568),major life events(OR=5.440,95%CI:3.987-6.896),and sleep disturbance(OR=1.989,95%CI:1.268-2.721)were risk factors for relapse in elderly patients with depression(P<0.05).Conclusion Relapse in elderly patients with depression is common in clinical practice,accompanied by physical disease,cognitive dysfunction,treatment compliance,major life events,and sleep disturbance are risk factors for relapse,and targeted interventions should be taken to reduce the relapse rate.
作者
吴婷婷
娄永翱
沈翠珍
WU Tingting;LOU Yongao;SHEN Cuizhen(School of Nursing,Zhejiang Chinese Medical University,Zhejiang Province,Hangzhou 310053,China;Ward Nine,Ningbo Kangning Hospital,Zhejiang Province,Ningbo 315201,China)
出处
《中国医药导报》
CAS
2022年第29期77-80,共4页
China Medical Herald
关键词
老年抑郁症
复发
躯体疾病
认知功能障碍
治疗依从性
重大生活事件
睡眠障碍
Geriatric depression
Recurrent attack
Somatic disease
Cognitive impairment
Therapeutic compliance
Major life events
Somnipathy
