摘要
目的认知行为治疗对老年抑郁症患者认知功能改善的影响。方法选取大连市第七人民医院老年精神科2017年10月~2018年6月收治的老年抑郁症患者80例,随机分为两组,实验组和对照组,各40例。实验组接受SSRI药物治疗+认知行为治疗(Cognitive Behavioral Therapy,CBT),对照组只接受SSRI药物治疗。两组患者治疗前后均进行简易智力状态检查量表(MMSE)、蒙特利尔认知功能评估量表(MOCA),对比两组患者治疗临床疗效及认知损害改善情况。结果实验组治疗前HADM评分与对照组比较差异无统计学意义(P>0.05),治疗后患者HAMD评分均较治疗前有明显下降,实验组治疗后HAMD评分(10.8±4.2)分,与对照组(11.3±4.4)分相比较差异无统计学意义(P>0.05);实验组治疗后MMSE、MOCA评分较治疗前明显提高(P<0.05);对照组MMSE、MOCA评分较治疗前差异无统计学意义(P>0.05)。两组之间治疗后比较,实验组MMSE、MOCA评分改善均优于对照组,差异有统计学意义(P<0.05)。结论SSRI药物联合认知行为治疗老年抑郁症较单纯使用SSRI药物治疗疗效更显著,老年抑郁症认知损害得到明显改善。
Objective Effects of cognitive behavioral therapy on cognitive function in elderly patients with depression.Methods 80 cases of depression were selected from the geriatric department of the seventh people’s hospital of dalian from October 2017 to June 2018,and were randomly divided into two groups,the experimental group and the control group,with 40 cases each.The experimental group received SSRI+Cognitive Behavioral Therapy(CBT),and the control group received SSRI.Before and after treatment,the simple mental status examination scale(MMSE)and MOCA were evaluated for the two groups of patients,and the clinical efficacy and cognitive impairment improvement of the two groups were compared.Results The HADM score of the experimental group before treatment points,and control group points compared with no significant difference(P>0.05),each time point after treatment of two patients with HAMD were significantly decreased compared with before treatment,after 3 month of treatment,the experimental group HAMD score(10.8±4.2)points,and control group(11.3±4.4)points phase difference was not significant(P>0.05)after treatment,the total MMSE score of experimental group significantly decreased compared with pretreatment(P<0.05);There was no significant difference in MMSE score in control group compared with pre-treatment(P>0.05).After treatment the improvement of MMSE and MOCA scores of experimental group were better than control group(P<0.05).Conclusions The effect of SSRI combined with cognitive behavior for treating elderly patients with depression is more significant than pure SSRI,which can significantly improve dysfunctional cognitive impairment and effectively relieve depressive symptoms.
作者
姚烨
杨春燕
许艳秋
焉双梅
YAO Ye;YANG Chunyan;XU Yanqiu(Dalian City 7th People's Hospital,Dalian 116000,China)
出处
《国际精神病学杂志》
2020年第1期67-70,共4页
Journal Of International Psychiatry
关键词
认知行为治疗
认知损害
老年抑郁症
Cognitive Behavioral Therapy
Dysfunctional cognitive impairment
Depression
