摘要
近距离放射治疗用^(125)I粒籽源具有低能、低剂量率的特点,基于绝对测量原理,利用现有的自由空气电离室无法实现空气比释动能强度的准确测量,因此设计了测量^(125)I粒籽源的空气比释动能强度专用的外推电离室。电离室的设计需要满足带电粒子平衡条件,通过蒙特卡罗模拟计算与理论分析对电离室的关键部件结构设计进行了研究,包括光阑、高压极、收集极、栅极及分压电阻等。设计的专用电离室采用锥形束照射方式,增加电离室的有效测量体积占比,相比自由空气电离室有效测量体积占比由0.3%提升至12%。采用电荷积分法对活度标称值为3.404×10^(7) Bq的6711型^(125)I粒籽源空气比释动能强度进行了测量,测量结果为1.250μGy·m^(2)·h^(-1)(U_(rel)=1.6%,k=2)。通过进一步优化设计,该外推电离室可用于粒籽源空气比释动能强度的量值复现,为建立近距离放疗剂量的量值传递体系提供技术基础。
A new physical quantity,air kerma strength,was proposed to replace the apparent activity of the brachytherapy source to characterize the source strength,which is reported by the American Association of Physicists in Medicine(AAPM)task group No.32 report.^(125)I seeds are widely used for interstitial brachytherapy treatment.It is very important to establish the primary standard to realize the traceability and transmission of the physical quantity.The existing primary standard free air chamber(FAC)can’t measure the air kerma strength of ^(125)I in a high accuracy,because of the characteristics of low energy and low dose rate of ^(125)I seeds.Therefore,a special ionization chamber was designed and manufactured for the realization of the absolute measurement of air kerma strength from a single ^(125)I seeds.In order to meet the basic requirement of ionization chamber design,that is charged particle balance,the structure design of key components of ionization chamber was studied by Monte Carlo and theoretical calculation,which included diaphragm,high voltage electrode,collecting electrode,potential rings,divider resistors,et al.A large conical beam irradiation was designed to increase the coverage of the measurement volume to increase the deposited energy of the secondary electrons.The distance between the high voltage electrode and the collecting electrode is 3-200 mm.The response of the ionization chamber with different thicknesses of high voltage electrode was determined by utilizing the MCNP code.The high voltage electrode was made of Al-coated polyethylene terephthalate(PET)foil.Two types of the collecting electrode of the ionization chamber were compared with the deposited energy in measurement volume.The type of the PET foil has a 0.07%effect of the deposited energy in the ionization chamber,and the type of the 1 cm PMMA sheet causes a 7.5%energy deposited change.Finally,the collecting electrode consists of a radius of 5 cm Al-coated PET foil with the width of 9 cm potential guard.The effect measurement volum
作者
刘川凤
李德红
王红玉
张健
杭仲斌
黄建微
倪宁
高惠波
刘蕴韬
宋明哲
LIU Chuanfeng;LI Dehong;WANG Hongyu;ZHANG Jian;HANG Zhongbin;HUANG Jianwei;NI Ning;GAO Huibo;LIU Yuntao;SONG Mingzhe(National Institute of Metrology,Beijing 100029,China;Key Laboratory of Measurement and Calibration Technology,China Institute of Atomic Energy,Beijing 102413,China;HTA Co.,Ltd.,Beijing 102413,China)
出处
《原子能科学技术》
EI
CAS
CSCD
北大核心
2022年第10期2195-2202,共8页
Atomic Energy Science and Technology
基金
中国计量科学研究院博后项目(BH2113)
中国原子能科学研究院基础科研项目(BJ19001112)。
