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儿童幽门螺旋杆菌感染治疗进展 被引量:2

Progress in the treatment of helicobacter pylori infection in children
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摘要 幽门螺旋杆菌于1982年由澳大利亚研究者首次发现,是一种寄生于人体胃内的细菌。临床研究发现,幽门螺旋杆菌为革兰阴性菌,属于微需氧菌,生长于35~37℃环境中。幽门螺旋杆菌感染临床发生率较高,该病属于传染性疾病,可发生于任何人,在儿童中也比较多见,该病感染率较高,和胃肠内外多种疾病具有密切的关系,对患儿健康造成了危害。目前,临床治疗儿童幽门螺旋杆菌感染多采取根除幽门螺旋杆菌相关治疗方法。既往临床采取传统三联疗法根除幽门螺旋杆菌感染,但其治疗效果并不理想,为了进一步提升临床治疗效果,彻底根除幽门螺旋杆菌,临床多采取含有铋剂的四联疗法、联合中医药以及益生菌等方法。而儿童感染幽门螺旋杆菌后更需谨慎选择治疗方式,若治疗方式不当,可能对患儿造成不可逆损伤,影响患儿生长发育,需及时采取有效方法对患儿进行治疗。多项研究指出,儿童感染幽门螺旋杆菌后多采取联合中药、益生菌等方式治疗,均取得了良好的效果。本文对儿童幽门螺旋杆菌的临床治疗进展进行综述,以期为儿童幽门螺旋杆菌感染的临床治疗提供帮助。 Helicobacter pylori is first discovered by Australian researchers in 1982.It is a bacterium parasitic in the human stomach.Clinical studies have found that helicobacter pylori is a gram-negative bacterium,belonging to micro aerobic bacteria,which grows in an environment of 35-37 ℃.The clinical incidence of helicobacter pylori infection is high.The disease is an infectious disease,which can occur in anyone,and it is also common in children.The infection rate of the disease is high,which is closely related to a variety of diseases inside and outside the gastrointestinal tract,causing harm to the health of children.At present,the clinical treatment of helicobacter pylori infection in children is mostly related to the eradication of helicobacter pylori.In the past,traditional triple therapy was used to eradicate helicobacter pylori infection,but its treatment effect was not ideal.In order to further improve the clinical treatment effect and completely eradicate helicobacter pylori,clinical methods such as quadruple therapy containing bismuth,combined with traditional Chinese medicine or probiotics were mostly used.However,children infected with helicobacter pylori need to choose the treatment method carefully.If the treatment method is inappropriate,it may cause irreversible damage to children and affect their growth and development.Effective methods should be taken in time to treat children.Many studies have pointed out that children infected with helicobacter pylori are often treated with the combination of traditional Chinese medicine or probiotics,which have achieved good results.This article reviews the clinical treatment progress of helicobacter pylori in children,in order to provide help for the clinical treatment of helicobacter pylori infection in children.
作者 李煜杰 LI Yu-jie(Department of Gastroenterology,Tianjin Binhai New Area Dagang Hospital,Tianjin 300270,China)
出处 《中国城乡企业卫生》 2022年第8期60-62,共3页 Chinese Journal of Urban and Rural Enterprise Hygiene
关键词 幽门螺旋杆菌感染 儿童 治疗 中药 益生菌 三联疗法 四联疗法 Helicobacter pylori infection Children Treatment Traditional Chinese medicine Probiotics Triple therapy Quadruple therapy
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