摘要
目的探讨儿童轮状病毒(rotavirus,RV)肠炎在腹泻病例中的构成比及危险因素。方法回顾性分析2019年1月—2020年12月我院小儿内科住院部收治的746例腹泻患儿病例资料,根据是否诊断为RV感染将患儿分为RV组和非RV组,分析比较两组基本特征、临床特点及生化指标,采用Logistic回归分析儿童感染RV的相关危险因素。结果感染RV构成比为53.62%;RV组患儿喂食前清洁手部、母乳喂养占比低于非RV组,存在RV接触史的比例显著高于非RV组,冬季发病占比显著高于非RV组占比,生化指标显著优于非RV组;喂食前未清洁手部、非母乳喂养、有RV患儿接触史、冬季是感染RV的危险因素。结论喂食前未清洁手部、非母乳喂养、有RV患儿接触史及冬季是儿童感染RV的危险因素。临床应积极开展针对家长的RV防治健康教育工作,对患儿做好隔离及环境消毒工作。
Objective To investigate the constituent ratio and risk factors of rotavirus(RV)enteritis among pediatric diarrhea patients.Methods The data of 746 pediatric cases of diarrhea admitted to the Pediatric Internal Medicine Department of our hospital from January 2019 to December 2020 were analyzed retrospective.The patients were divided into RV group and non-RV group according to RV infection.The basic characteristics,clinical characteristics and biochemical indexes of the two groups were analyzed and compared.Logistic regression was used to analyze the risk factors of RV infection in children.Results The constituent ratio of RV infection was 53.62%;The proportion of cleaning hands before feeding and breastfeeding in RV group was lower than that in non-RV group.The proportion of children with RV exposure history in RV group was significantly higher than that in non-RV group.The incidence rate in winter in RV group was significantly higher than that in non-RV group,and biochemical indexes were significantly better than those in non-RV group.Not-cleaning hands before feeding,non-breastfeeding,exposure history of children with RV and winter were the risk factors for RV infection.Conclusions Not-cleaning hands before feeding,non-breastfeeding,exposure history of children with RV and winter were independent risk factors for RV infection in children.Health education about RV prevention and treatment for parents should be actively carried out.The infected children should be quarantined and the environment should be disinfected.
作者
贾伟
杨东
解俊章
房海霞
Jia Wei;Yang Dong;Xie Junzhang;Fang Haixia(Department of Preventive Health Care,Zhoucun District Maternal and Children’s Health Hospital of Zibo City,Zibo 255300,China;Department of Pediatrics,Zhoucun District Maternal and Children’s Health Hospital of Zibo City,Zibo 255300,China)
出处
《国际病毒学杂志》
2022年第4期330-333,共4页
International Journal of Virology
关键词
儿童轮状病毒
构成比
危险因素
肌酸激酶同工酶
Rotavirus in children
Composition rate
Risk factors
Creatine kinase isoenzyme