摘要
目的 探讨女性发生早期乳腺癌的危险因素及防控措施。方法 回顾性选取2017年9月至2021年3月间上海市宝山区仁和医院收治的50例早期乳腺癌患者为早期乳腺癌组,选取同期健康体检的50例健康女性为健康组。对两组受试者临床资料进行单因素分析,将有统计学意义的因素进行多因素Logistic回归分析,筛选出独立危险因素。结果 女性早期乳腺癌组患者体质量指数(BMI)≥25、初潮年龄<13岁、有乳腺增生、长期口服避孕药、精神压抑、无饮茶习惯及无哺乳史均多于健康组,差异均有统计学意义(P<0.05)。以女性发生早期乳腺癌为因变量,将单因素分析中差异有统计学意义的指标作为自变量,结果显示,BMI≥25、初潮年龄<13岁、有乳腺增生、长期口服避孕药、精神压抑、无饮茶习惯及无哺乳史为女性发生早期乳腺癌的危险因素(均P<0.05)。结论 BMI≥25、初潮年龄<13岁、有乳腺增生、长期口服避孕药、精神压抑、无饮茶习惯及无哺乳史为女性发生早期乳腺癌的危险因素,可通过减轻体重、提早对女童规律饮食、定期体检、规范使用避孕药、保持心情开朗、培养饮茶习惯及哺乳等措施,降低癌变可能。
Objective To study the risk factors and prevention and control measures for early stage breast cancer in women. Methods A retrospective analysis of the clinical data was conducted in 50 patients with early stage breast cancer who received treatment(early stage breast cancer group) and 50 healthy individuals who underwent physical examination(healthy group) at Renhe Hospital from September 2017 to March 2021. Univariate analysis was performed using clinical data of all participants. Multivariate Logistic analysis was conducted then for those of statistical interest to determine independent risk factors. Results The proportion of patients with body mass index(BMI)≥25, age of menarche<13 years old, breast hyperplasia, long-term oral contraceptives, mental depression, non-tea habit, and breastfeeding history was significantly higher in the early stage breast cancer group than in the healthy group, and the difference was statistically significant(all P<0.05). Multivariate Logistic regression analysis showed that BMI≥25, age of menarche <13 years, breast hyperplasia, long-term oral contraceptives, mental depression, non-tea drinking habits, and non-breastfeeding history are risk factors for early stage breast cancer in women when the occurrence of early stage breast cancer was considered as a dependent variable and factors of statistical interest in the univariate analysis was considered as dependent variables(all P<0.05). Conclusion BMI≥25, age of menarche <13 years, breast hyperplasia, long-term oral contraceptives, mental depression, non-tea drinking habits, and non-breastfeeding history are risk factors for early stage breast cancer in women. Measures such as weight loss, regular diet, regular physical examination, standardized use of contraceptives, keeping a cheerful mood, developing tea drinking habits, and breastfeeding can reduce the possibility of cancer.
作者
陈原华
周冬
CHEN Yuan-hua;ZHOU Dong(Department of General Surgery,Renhe Hospital,Baoshan District,Shanghai 201901,China)
出处
《中国肿瘤临床与康复》
2022年第9期1070-1072,共3页
Chinese Journal of Clinical Oncology and Rehabilitation
关键词
乳腺肿瘤
早期
危险因素
防控措施
Breast neoplasms
Early stage
Risk factors
Prevention and control measures
