摘要
目的比较双相情感障碍(BD)患者和家属对BD前驱症状的识别能力。方法回顾性调查2015年3月至2018年9月首都医科大学附属北京安定医院门诊和住院部收治的80例非急性期BD患者以及与患者密切接触的80名家属(照料者/监护人)。采用BD前驱症状回顾性量表(BPSS-R)对研究对象进行半结构式访谈,比较患者、家属对前驱症状的识别能力。结果80例患者中,BD-Ⅰ型占73.8%(59/80),BD-Ⅱ型占26.2%(21/80);女性占35.0%(28/80);首次发作症状为抑郁的患者占38.8%(31/80),前驱期发作病程为(7.1±3.4)个月;首次发作症状为轻躁狂/躁狂的患者占61.2%(49/80),前驱期发作病程为(6.1±3.6)个月。当首次发作为抑郁发作时,家属对社会孤立、学业和职业功能不良、焦虑/紧张、注意力不集中、思维混乱或奇怪的想法的识别率高于患者,评估学校/工作问题的严重程度高于患者,差异有统计学意义(P<0.05)。当首次发作为轻躁狂/躁狂发作时,家属对社会孤立、焦虑/紧张、运动迟缓、失眠、体重或食欲下降、事物的愉快感或兴趣丧失的识别率高于患者,差异有统计学意义(P<0.05)。无论首次发作是抑郁还是轻躁狂/躁狂发作,患者对抑郁心境的识别率高于家属,差异有统计学意义(P<0.01)。结论BD患者和家属对于BD前驱症状的识别能力存在差异,家属对除抑郁心境外的其他多个前驱症状的识别能力高于患者。
Objective To compare the recognition ability of different prodromal symptoms of bipolar disorder(BD) among BD patients and their caregivers.Methods A retrospective survey was conducted on80 non-acute BD patients admitted to the outpatient and inpatient departments of Beijing Anding Hospital Affiliated to Capital Medical University from March 2015 to September 2018 and 80 family members(caregivers/guardians) who had close contact with the patients.Semi-structured interviews were conducted with all the study object using Bipolar Prodrome Symptom Scale-Retrospective(BPSS-R) scale,to compare the recognition ability of prodromal symptoms between the patients and caregivers.Results Of the 80 patients,73.8%(59/80) were BD-Ⅰ and 26.2%(21/80) were BD-Ⅱ,35.0%(28/80) were female,38.8%(31/80) of the patients had the first symptom of depression with(7.1±3.4) months’ duration of the prodromal episode,61.2%(49/80) of the patients had the first symptom of(hypo) mania with(6.1±3.6) months’ duration of the prodromal episode.When the first episode of depression occurred,the recognition rates of family members for social isolation,academic and occupational dysfunction,anxiety or nervousness,trouble concentration,strange or unusual ideas were higher than that of the patients,and the severity of educational and occupational dysfunction was higher than that of the patients,and the differences were statistically significant(P<0.05).Within the first episode of(hypo) mania,the recognition rates of family members for social isolation,anxiety or nervousness,physically slowed down,insomnia,weight loss or decreasing in appetite,reduction of enjoyment or interest were higher than that of the patients,and the differences were statistically significant(P <0.05).Regardless of whether the first episode was depression or(hypo)mania,the patients’ recognition rate of depression was significantly higher than that of caregivers(P < 0.01).Conclusions There are differences in the recognition ability of bipolar prodromal symptoms between patie
作者
郭彤
谢小萌
沙莎
周勇
乔羽
李晓虹
Guo Tong;Xie Xiaomeng;Sha Sha;Zhou Yong;Qiao Yu;Li Xiaohong(The National Clinical Research Center for Mental Disorders&Beijing Key Laboratory of Mental Diseases,Beijing Anding Hospital,Capital Medical University,Beijing 100088,China)
出处
《神经疾病与精神卫生》
2022年第9期623-628,共6页
Journal of Neuroscience and Mental Health
基金
北京市研究型病房建设(BCRW202009)
北京市科技计划项目(Z151100004015042)。
关键词
双相情感障碍
前驱症状
识别能力
家属
Bipolar disorder
Prodromal symptoms
Recognition ability
Family members
