摘要
目的探究分析无创双水平气道正压通气在治疗重症支气管哮喘中的应用价值。方法以2017年7月—2021年7月院内接治的78例重症支气管哮喘患者为研究对象,根据不同治疗方法将患者分为参考组和研究组,每组39例。两组患者入院后均予以相同的吸氧、雾化吸入等治疗,参考组静脉滴注氨茶碱氯化钠注射液,研究组在参考组基础上增加呼吸机无创双水平气道正压通气治疗。对比分析治疗前后血气指标、肺功能及治疗效果。结果治疗后,研究组动脉血氧分压(PaO_(2))及血氧饱和度(SaO_(2))指标分别为(85.79±6.53)mmHg、(95.84±3.65)%,高于参考组;研究组动脉血二氧化碳分压(PaCO_(2))为(45.12±7.13)mmHg,低于参考组,差异有统计学意义(t=5.125、5.841、8.984,P<0.05)。治疗后,研究组用力肺活量(FVC)、一秒用力呼气容积(FEV1)、FEV1/FVC指标分别为(3.57±0.79)L、(2.77±0.51)L和(78.86±5.13)%,均高于参考组,差异有统计学意义(t=2.026、3.686、5.585,P<0.05)。研究组时间总有效率为94.87%,高于参考组79.49%,差异有统计学意义(χ^(2)=4.129,P<0.05)。结论针对重症支气管哮喘患者的治疗中,在常规治疗基础上增加无创双水平气道正压通气治疗可有效改善其肺功能及血气指标,促进预后恢复。
Objective To explore and analyze the application value of non-invasive bilevel positive airway pressure ventilation in the treatment of severe bronchial asthma.Methods A total of 78 patients with severe bronchial asthma who were admitted to the hospital from July 2017 to July 2021 were selected as the research objects.According to different treatment methods,the patients were divided into reference group and study group,with 39 cases in each group.The two groups of patients were given the same oxygen inhalation,atomization inhalation and other treatments after admission,and the reference group was intravenously infused with aminophylline and sodium chloride injection.On the basis of the reference group,the study group added ventilator non-invasive bilevel positive airway pressure therapy.The blood gas indexes,pulmo⁃nary function before and after treatment and therapeutic effect were compared and analyzed.Results After treatment,the arterial partial pres⁃sure of oxygen(PaO_(2))and oxygen saturation(SaO_(2))in the study group were(85.79±6.53)mmHg and(95.84±3.65)%,respectively,which were higher than those in the reference group;the arterial partial pressure of carbon dioxide in the study group(PaCO_(2))was(45.12±7.13)mmHg,which was lower than the reference group,and the difference was statistically significant(t=5.125,5.841,8.984,P<0.05).After treatment,the indexes of forced vital capacity(FVC),forced expiratory volume in one second(FEV1)and FEV1/FVC in the study group were(3.57±0.79)L,(2.77±0.51)L and(78.86±5.13)%,respectively,which were higher than in the reference group,the difference was statistically significant(t=2.026,3.686,5.585,P<0.05);The total effective rate of the study group was 94.87%higher than that of the reference group 79.49%,the difference was statistically significant(χ^(2)=4.129,P<0.05).Conclusion In the treatment of patients with severe bronchial asthma,the addition of non-invasive bilevel positive airway pressure therapy on the basis of conventional treatment can effectively improve
作者
可爱华
史淑静
郭军
孙爱华
王文婷
颜卫峰
KE Aihua;SHI Shujing;GUO Jun;SUN Aihua;WANG Wenting;YAN Weifeng(Department of Respiratory and Critical Care Medicine,Haidian Hospital,Beijing,100029 China;Department of Respiratory and Critical Care Medicine,Beijing Tsinghua Chang Gung Hospital Affiliated to Tsinghua University,Beijing,102218 China;Department of Respiratory and Critical Care Medicine,Beijing China-Japan Friendship Hospital,Beijing,100081 China;Department of Rehabilitation,Haidian Hospital,Beijing,100029 China)
出处
《世界复合医学》
2022年第6期72-76,共5页
World Journal of Complex Medicine
关键词
重症支气管哮喘
呼吸机
肺功能
血气指标
治疗效果
Severe bronchial asthma
Ventilator
Pulmonary function
Blood gas index
Therapeutic effect
