摘要
作为典型的身心疾病,哮喘多表现为本虚标实或者虚实夹杂,它不仅会影响患者的身心健康,还可能引发严重的社会问题,近年来其发病率的不断升高,逐渐引起了学者们的广泛关注。中医肾藏涵盖了HPA轴功能,文章通过HPA轴完整的作用环路分析,对中医肾藏的功能剖析,哮喘发病的中医及西医机制以及各学者研究发现通过补肾调节HPA轴的举例分析,得出哮喘的不同阶段都存在HPA轴功能紊乱,哮喘发病的根本机制之一为肾虚,认为“治喘须治肾”,补肾药物作用的靶点可能为下丘脑。临床通过辨证论治,分清虚实侧重,治疗及时得当,可提高疗效,缩短病程。通过治肾以改善HPA轴紊乱,可减少支气管哮喘的发作。
Asthma,as a typical physical and mental disease,the clinical this deficiency sign is obviously solid,card of the actual situation mixture.It will not only affect the physical and mental health of patients,but also may cause serious social problems.In recent years,the increasing incidence of asthma has gradually attracted extensive attention from scholars.The article analyses the role of hypothalamuspituitary-adrenal axis(HPA axis)complete loop,TCM anatomy of renal function,the pathogenesis of asthma mechanism of traditional Chinese medicine and Western medicine,examples and analysis of various scholars’findings on tonifying kidney and regulating HPA axis,It is concluded that there are HPA axis dysfunction in different stages of asthma and one of the fundamental mechanisms of asthma is kidney deficiency,think“cure asthma must cure kidney”,through the treatment based on syndrome differentiation,distinguish the actual situation,timely and proper treatment,can improve the curative effect,shorten the course of the disease.Tonifying kidney treatment to improve the HPA axis disorder can reduce the onset of bronchial asthma.
作者
刘芳
徐丽
LIU Fang;XU Li(Liaoning University of Traditional Chinese Medicine,Shenyang 110847,Liaoning,China;Second Affiliated Hospital of Liaoning University of Traditional Chinese Medicine,Shenyang 110034,Liaoning,China)
出处
《辽宁中医药大学学报》
CAS
2022年第5期66-69,共4页
Journal of Liaoning University of Traditional Chinese Medicine
基金
国家自然科学基金(81603511)。
关键词
哮喘
HPA轴
肾虚
补肾益气
下丘脑
asthma
HPA axis
kidney deficiency
tonifying kidney and invigorating Qi
hypothalamus
